N-Ethyltetrahydrofurfurylamine

Base Information

• Chemical Name: N-Ethyltetrahydrofurfurylamine
• CAS No.: 7179-86-4
• Molecular Formula: C7H15 N O
• Molecular Weight: 129.202
• Hs Code.: 2932190090
• European Community (EC) Number: 230-543-0
• NSC Number: 97515
• DSSTox Substance ID: DTXSID601291355
• Nikkaji Number: J28.140I
• Mol file: 7179-86-4.mol

Synonyms:7179-86-4;N-Ethyltetrahydrofurfurylamine;N-(oxolan-2-ylmethyl)ethanamine;N-(TETRAHYDRO-2-FURANYLMETHYL)-1-ETHANAMINE;N-((Tetrahydrofuran-2-yl)methyl)ethanamine;N-(tetrahydrofuran-2-ylmethyl)ethanamine;EINECS 230-543-0;N-Ethyltetrahydro-2-furanmethanamine;ethyl(oxolan-2-ylmethyl)amine;N-(tetrahydro-2-furanylmethyl)ethanamine;NSC97515;SCHEMBL2448784;ethyl[(oxolan-2-yl)methyl]amine;DTXSID601291355;MFCD00069031;NSC 97515;NSC-97515;AKOS000153035;AKOS016352353;BS-38422;CS-0251503;EN300-54940

Chemical Property of N-Ethyltetrahydrofurfurylamine

Chemical Property:

• Vapor Pressure: 1.04mmHg at 25°C
• Boiling Point: 177.4°C at 760 mmHg
• PKA: 9.74±0.10(Predicted)
• Flash Point: 64.1°C
• PSA: 21.26000
• Density: 0.905g/cm³
• LogP: 1.16580
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 129.115364102
• Heavy Atom Count: 9
• Complexity: 75.3

Purity/Quality:

98%min ^*data from raw suppliers

N-(Tetrahydrofuran-2-ylmethyl)ethanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCNCC1CCCO1

Technology Process of N-Ethyltetrahydrofurfurylamine

There total 5 articles about N-Ethyltetrahydrofurfurylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

→ N-((tetrahydrofuran-2-yl)methyl)ethanamine (7179-86-4)

Guidance literature:

Reference yield: 53.0%

Tetrahydrofurfuryl alcohol (97-99-4) + acetonitrile (75-05-8,26809-02-9) → 1-ethyl-piperidine (766-09-6) + N-((tetrahydrofuran-2-yl)methyl)ethanamine (7179-86-4)

Guidance literature:

With hydrogen; magnesium oxide; copper; at 230 ℃; under 11400 Torr;

DOI:10.1007/BF00475557

Reference yield: 53.0%

Tetrahydrofurfuryl alcohol (97-99-4) + acetonitrile (75-05-8,26809-02-9) → 1-ethyl-piperidine (766-09-6) + N-((tetrahydrofuran-2-yl)methyl)ethanamine (7179-86-4)

Guidance literature:

With hydrogen; magnesium oxide; copper; at 230 ℃; under 11400 Torr; Mechanism; Product distribution; other catalysts; other temperature; other pressure;

DOI:10.1007/BF00475557

upstream raw materials:

Tetrahydrofurfuryl chloride

ethylamine

furfural

Tetrahydrofurfuryl alcohol

Downstream raw materials:

tert-butyl 4-(ethyl((tetrahydrofuran-2-yl)methyl)amino)-2-(4-(2-methyl-1H-imidazol-1-yl)phenylamino)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate

tert-butyl 4-(ethyl((tetrahydrofuran-2-yl)methyl)amino)-2-(4-(oxazol-5-yl)phenylamino)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate

((2-bromo-4-isopropyl-phenyl)-{4-[ethyl-(tetrahydro-furan-2-ylmethyl)-amino]-6-methyl-3-nitro-pyridin-2-yl}-amino)-acetic acid ethyl ester

N²-(2-bromo-4-isopropyl-phenyl)-N⁴-ethyl-6-methyl-3-nitro-N⁴-(tetrahydro-furan-2-ylmethyl)-pyridine-2,4-diamine

Refernces

• 1、 Kozintsev, S. I.,Basalaeva, L. I.,Gladkikh, L. V.,Kozlov, N. S.. "Catalytic Hydroamination of Furfuryl and Tetrahydrofurfuryl Alcohols with Nitriles". . p. 19 - 21. Retrieved 2007/10/02.