2-Methoxybenzaldehyde oxime

Base Information

• Chemical Name: 2-Methoxybenzaldehyde oxime
• CAS No.: 29577-53-5
• Molecular Formula: C8H9NO2
• Molecular Weight: 151.165
• Hs Code.: 2928000090
• European Community (EC) Number: 659-878-4
• Mol file: 29577-53-5.mol

Synonyms:2-Methoxybenzaldehyde oxime;o-Anisaldehyde oxime;o-Methoxybenzaldehyde oxime;29577-53-5;2-Methoxy-benzaldehyde oxime;2-Methoxybenzaldoxime;54582-20-6;N-[(2-methoxyphenyl)methylidene]hydroxylamine;(NE)-N-[(2-methoxyphenyl)methylidene]hydroxylamine;e-o-methoxybenzaldehyde oxime;2-Methoxybenzaldehyde oxime #;(E)-2-Methoxybenzaldehydeoxime;(E)-2-Methoxybenzaldehyde oxime;Benzaldehyde, 2-methoxy-, oxime;CBQNSTKQBGIAEL-RMKNXTFCSA-N;HMS1783K02;AMY25121;MFCD00016407;NSC 27015;AKOS000303845;JS-3024;NCGC00323595-01;CS-0316247;EN300-05938;AB01319155-02;(E)-N-[(2-methoxyphenyl)methylidene]hydroxylamine;A819965;Z49568534

Chemical Property of 2-Methoxybenzaldehyde oxime

Chemical Property:

• Vapor Pressure: 0.00706mmHg at 25°C
• Melting Point: 100-101 °C
• Refractive Index: 1.51
• Boiling Point: 258.3 °C at 760 mmHg
• PKA: 10.75±0.10(Predicted)
• Flash Point: 110 °C
• PSA: 41.82000
• Density: 1.07 g/cm³
• LogP: 1.50330
• XLogP3: 2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 151.063328530
• Heavy Atom Count: 11
• Complexity: 136

Purity/Quality:

99% ^*data from raw suppliers

2-MethoxybenzaldehydeOxime ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=CC=C1C=NO
• Isomeric SMILES: COC1=CC=CC=C1/C=N/O

Technology Process of 2-Methoxybenzaldehyde oxime

There total 12 articles about 2-Methoxybenzaldehyde oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

ortho-anisaldehyde (135-02-4) → 2-Methoxy-benzaldehyde oxime (29577-53-5)

Guidance literature:

With hydroxylamine hydrochloride; silica gel; for 0.0333333h;

DOI:10.1080/00397919908086156

Reference yield: 92.0%

(2-methoxyphenyl)methanol (612-16-8) → 2-Methoxy-benzaldehyde oxime (29577-53-5)

Guidance literature:

(2-methoxyphenyl)methanol; With dihydrogen peroxide; at 20 ℃; for 0.166667h; Green chemistry;

With hydroxylamine hydrochloride; for 4.2h; Catalytic behavior; Green chemistry;

DOI:10.1016/j.molstruc.2019.03.008

Reference yield: 92.0%

2-methoxybenzylamine (6850-57-3) → 2-Methoxy-benzaldehyde oxime (29577-53-5)

Guidance literature:

With diperoxydodecanedioic acid; In N,N-dimethyl-formamide; at 20 - 55 ℃; for 0.333333h;

DOI:10.1039/c5nj00801h

upstream raw materials:

ortho-anisaldehyde

1-Nitropropane

nitromethane

methoxybenzene

Downstream raw materials:

2-Methoxy-benzaldehyde O-(5-chloro-2,4-dinitro-phenyl)-oxime

Acetic acid (2S,4S,5R,6R)-4,5-diacetoxy-6-acetoxymethyl-2-(5-chloro-N-hydroxy-2-methoxy-benzimidoylsulfanyl)-tetrahydro-pyran-3-yl ester

4-nitro-phenol

ethyl 3-(2-methoxyphenyl)-5-methylisoxazole-4-carboxylate

Refernces

• 1、 Laamari, Yassine,Auhmani, Aziz,Saadi, Mohamed,Ammari, Lahcen El,Khouili, Mostafa,Itto, My Youssef Ait,Auhmani, Abdelwahed,Ketatni, El Mostafa. "Synthesis, crystal structure, DFT studies and Hirshfeld surface analysis of novel isoxazole derivatives". . . Retrieved 2021.
• 2、 Pan, Hongmei,Lu, Tong,Wu, Xuedan,Gu, Chengwen,Tao, Naili,Zhang, Biao,Wang, Ao,Chen, Guangmei,Zhang, Kehua,Cheng, Jie,Jin, Jie. "Design and synthesis of sinomenine isoxazole derivatives via 1,3-dipolar cycloaddition reaction". supporting information. p. 2360 - 2364. Retrieved 2019/11/11.