612-16-8

Basic information

• Product Name: 2-Methoxybenzyl alcohol
• Synonyms: AKOS BBS-00004611;2-ANISYL ALCOHOL;2-ANISE ALCOHOL;2-ANISIC ALCOHOL;2-METHOXYBENZYL ALCOHOL;RARECHEM AL BD 0022;O-ANISYL ALCOHOL;O-ANISE ALCOHOL
• CAS NO: 612-16-8
• Molecular Formula: C₈H₁₀O₂
• Molecular Weight: 138.16
• EINECS: 210-296-5
• Product Categories: Benzhydrols, Benzyl & Special Alcohols;Aromatic compound;Alcohols;Anisoles, Alkyloxy Compounds & Phenylacetates;Building Blocks;C7 to C8;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds
• Mol File: 612-16-8.mol
• Article Data: 188

Chemical Properties

• Melting Point: 85-86 °C
• Boiling Point: 248-250 °C(lit.)
• Flash Point: >230 °F
• Appearance: Clear colorless to light orange-brown/Liquid
• Density: 1.039 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.572Pa at 25℃
• Refractive Index: n20/D 1.547(lit.)
• Storage Temp.: Store below +30°C.
• PKA: 14.43±0.10(Predicted)
• Water Solubility: Not miscible or difficult to mix in water. Soluble in ethanol.
• BRN: 2043673
• CAS DataBase Reference: 2-Methoxybenzyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methoxybenzyl alcohol(612-16-8)
• EPA Substance Registry System: 2-Methoxybenzyl alcohol(612-16-8)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 36/37/38-22
• Safety Statements: 23-24/25-37/39-26-36
• WGK Germany: 3
• F: 9-23
• TSCA: Yes
• Hazardous Substances Data: 612-16-8(Hazardous Substances Data)

Usage

Chemical Properties

Colorless to light yellow liqui

Synthesis Reference(s)

Tetrahedron Letters, 32, p. 5629, 1991 DOI: 10.1016/0040-4039(91)80103-D

Flammability and Explosibility

Notclassified

InChI:InChI=1/C8H10O2/c1-10-8-5-3-2-4-7(8)6-9/h2-5,9H,6H2,1H3

Upstream product

• 135-02-4 ortho-anisaldehyde 
• 579-75-9 2-Methoxybenzoic acid 
• 18483-89-1 2-(2-methoxybenzyloxy)tetrahydro-2H-pyran 
• 201230-82-2 carbon monoxide 
• 100-66-3 methoxybenzene 
• 21615-34-9 2-Methoxybenzoyl chloride 
• 31600-86-9 2-methoxyphenyllithium 
• 195064-77-8 2-methoxybenzyl trimethylsilyl ether 
• 870-63-3 prenyl bromide 
• 97-93-8 triethylaluminum 
• 100-46-9 benzylamine 
• 90-02-8 salicylaldehyde 
• 930-30-3 cyclopent-2-enone 
• 62-53-3 aniline 

Downstream Products

• 115893-22-6 (2-methoxy-benzyl)-(tri-O-acetyl-2-acetylamino-2-deoxy-β-D-glucopyranoside) 
• 130716-94-8 4-(2-cyano-2-methylethyl)-2-methoxybenzyl alcohol 
• 76640-59-0 N,N-dimethyl 2-(3'-methoxy-2'-methylphenyl)-acetamide 
• 80909-99-5 2-(2-Methoxy-benzyloxymethyl)-oxirane 
• 40886-85-9 N-cyclohexyl-N-(cyclohexylcarbamoyl)propiolamide 
• 131530-53-5 2-methoxy benzyl propynoate 
• 127042-08-4 2-(2-methoxybenzyloxy)-2-methyl-4H-1,3-benzodioxin-4-one 
• 321430-43-7 2-(2-methoxybenzyloxy)isoindoline-1,3-dione 
• 134681-71-3 3-(2'-methoxybenzyloxy)prop-1-ene 
• 78358-12-0 methanesulfonic acid 2-methoxy-benzyl ester 
• 5819-93-2 2,2'-dimethoxydiphenylmethane 
• 81245-46-7 1-methoxy-2-(iodomethyl)benzene 
• 18483-89-1 2-(2-methoxybenzyloxy)tetrahydro-2H-pyran 
• 35480-25-2 o-methoxybenzyl acetate 

Relevant articles and documents

Heterobimetallic tin(II) oxido clusters of the type [{Sn6(μ3-O)4(μ3-OCH2R)4} {W(CO)5}4] and [{Sn5(μ3-O)2(μ-OCH2R)4(μ3-OCH2R)2}{Fe(CO)4}2]

Reaction of the tin(II) alkoxides bis(2-methoxyphenylmethanolate)tin(II) (1) and bis(2,4-dimethoxyphenylmethanolate)tin(II) (2) with [W(CO)5(thf)] and [Fe2(CO)9], respectively, gave the heterobimetallic tin(II) oxido clusters [{Sn6(μ3-O)4(μ3-OCH2R)4}{W(CO)5}4] [3, R[dbnd6]C6H4(OCH3)-2); 4, R[dbnd6]C6H3(OCH3)2-2,4] and [{Sn5(μ3-O)2(μ-OCH2R)4(μ3-OCH2R)2}{Fe(CO)4}2] [5, R[dbnd6]C6H3(OCH3)2-2,4] which were isolated reproducibly with fair yield as a result of partial hydrolysis in the presence of moisture. The metal oxido clusters are composed of polynuclear tin(II) oxido cages entrapped by arylmethanolato ligands and coordinated to metal carbonyl moieties via lone pairs of electrons at tin. The compounds were analyzed by single crystal X-ray diffraction analysis (1, 4·2THF and 5), elemental analyses, ATR-IR spectroscopy and1H,13C{1H} and119Sn{1H) NMR spectroscopy in solution as well as in solid state.

Sodium Aminodiboranate, a New Reagent for Chemoselective Reduction of Aldehydes and Ketones to Alcohols

Sodium aminodiboranate (NaNH 2(BH 3) 2, NaADBH) is a new member of the old borane family, which exhibits superior performance in chemoselective reduction. Experimental results show that NaADBH can rapidly reduce aldehydes and ketones to the corresponding alcohols in high efficiency and selectivity under mild conditions. There are little steric and electronic effects on this reduction.

KB3H8: An environment-friendly reagent for the selective reduction of aldehydes and ketones to alcohols

Selective reduction of aldehydes and ketones to their corresponding alcohols with KB3H8, an air- and moisture-stable, nontoxic, and easy-to-handle reagent, in water and THF has been explored under an air atmosphere for the first time. Control experiments illustrated the good selectivity of KB3H8 over NaBH4 for the reduction of 4-acetylbenzaldehyde and aromatic keto esters. This journal is