18483-89-1

Basic information

• Product Name: 2H-Pyran, tetrahydro-2-[(2-methoxyphenyl)methoxy]-
• CAS NO: 18483-89-1
• Molecular Formula: C13H18O3
• Molecular Weight: 222.284
• Mol File: 18483-89-1.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 2H-Pyran, tetrahydro-2-[(2-methoxyphenyl)methoxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Pyran, tetrahydro-2-[(2-methoxyphenyl)methoxy]-(18483-89-1)
• EPA Substance Registry System: 2H-Pyran, tetrahydro-2-[(2-methoxyphenyl)methoxy]-(18483-89-1)

Safety Data

• Hazardous Substances Data: 18483-89-1(Hazardous Substances Data)

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 612-16-8 (2-methoxyphenyl)methanol 

Downstream Products

• 612-16-8 (2-methoxyphenyl)methanol 
• 144176-14-7 5-(2-Methoxy-benzyloxy)-pentan-1-ol 
• 1233518-03-0 2-methoxybenzyl thiocyanate 
• 135-02-4 ortho-anisaldehyde 

Relevant articles and documents

Simple, facile and highly selective tetrahydropyranylation of alcohols using silica chloride

A simple and efficient process for tetrahydropyranylation of alcohols has been developed by reacting with dihydropyran at room temperature in presence of catalytic amount of silica chloride. The process is highly selective for monoprotection of the hydroxyl groups of symmetric diols.

Selective tetrahydropyranylation of alcohols and phenols using titanium(IV) salophen trifluoromethanesulfonate as an efficient catalyst

Titanium(IV) salophen trifluoromethanesulfonate, [TiIV(salophen)(OSO2CF3)2], as a catalyst enables selective tetrahydropyranylation of alcohols and phenols with 3,4-dihydro-2H-pyran. Using this catalytic system, primary, secondary and tertiary alcohols, as well as phenols, were converted to their corresponding tetrahydropyranyl ethers in high yields and short reaction times at room temperature. Investigation of the chemoselectivity of this method showed discrimination between the activity of primary alcohols in the presence of secondary and tertiary alcohols and phenols. This heterogenized catalyst could be reused several times without loss of its catalytic activity. Copyright

Highly efficient protection of alcohols and phenols catalysed by tin porphyrin supported on MIL-101

The catalytic activity of 5,10,15,20-tetrakis(4-aminophenyl)porphyrinatotin(IV) trifluoromethanesulfonate, [SnIV(TNH2PP)(OTf)2], supported on chloromethylated MIL-101, was investigated in the trimethylsilylation of alcohols and phenols with hexamethyldisilazane (HMDS) and also their tetrahydropyranylation with 3,4-dihydro-2H-pyran. Excellent yields, mild reaction conditions, short reaction times and reusability of the catalyst without significant decrease in its initial activity are noteworthy advantages of this supported catalyst.