p,p-Dimethylphosphine-borane

Base Information

• Chemical Name: p,p-Dimethylphosphine-borane
• CAS No.: 4268-35-3
• Molecular Formula: C2H7BP+
• Molecular Weight: 72.86
• Mol file: 4268-35-3.mol

Synonyms:p,p-Dimethylphosphine-borane;4268-35-3

Chemical Property of p,p-Dimethylphosphine-borane

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 73.0378424
• Heavy Atom Count: 4
• Complexity: 29

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: B=[P+](C)C

Technology Process of p,p-Dimethylphosphine-borane

There total 2 articles about p,p-Dimethylphosphine-borane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

sodium tetrahydroborate (16940-66-2) + dimethyl phosphine oxide (7211-39-4) → dimethylphosphine-borane (4268-35-3)

Guidance literature:

With lithium aluminium tetrahydride; cerium(III) chloride; In tetrahydrofuran; at 0 - 20 ℃; for 18h;

Reference yield:

chlorodimethylphosphine (811-62-1) → dimethylphosphine-borane (4268-35-3)

Guidance literature:

With lithium aluminium tetrahydride; dimethylsulfide borane complex; Inert atmosphere;

DOI:10.1021/jo300910w

Reference yield: 96.0%

dimethylphosphine-borane (4268-35-3) + 2,6-dichlorophenyl 2-diazo-2-m-tolylacetate → (+)-2,6-dichlorophenyl 2-(dimethylphosphine-boryl)-2-m-tolylacetate

Guidance literature:

With Cu(MeCN)₄PF₆; C₃₄H₂₈N₂O₂; sodium tetrakis[(3,5-di-trifluoromethyl)phenyl]borate; In dichloromethane; at 25 ℃; for 4h; enantioselective reaction; Inert atmosphere; Schlenk technique;

DOI:10.1021/ja408306a

upstream raw materials:

chlorodimethylphosphine

sodium tetrahydroborate

dimethyl phosphine oxide

Downstream raw materials:

(2-bromophenyl)-dimethylphosphine borane

Refernces

• 1、 -. "ANTI-BACTERIAL COMPOUNDS". Page/Page column 94-95. . Retrieved 2017/06/28.
• 2、 -. "ALKYNYL PHOSPHINE GOLD COMPLEXES FOR TREATING BACTERIAL INFECTIONS". Page/Page column 93. . Retrieved 2017/08/01.