(2-bromophenyl)-dimethylphosphine borane

Base Information

• Chemical Name: (2-bromophenyl)-dimethylphosphine borane
• CAS No.: 1383686-32-5
• Molecular Formula: C₈H₁₃BBrP
• Molecular Weight: 230.88
• Mol file: 1383686-32-5.mol

Synonyms:

Chemical Property of (2-bromophenyl)-dimethylphosphine borane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2-bromophenyl)-dimethylphosphine borane

There total 2 articles about (2-bromophenyl)-dimethylphosphine borane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

dimethylphosphine-borane (4268-35-3) + 2,3-dibromobenzene (583-53-9) → (2-bromophenyl)-dimethylphosphine borane (1383686-32-5)

Guidance literature:

dimethylphosphine-borane; With n-butyllithium; In tetrahydrofuran; at -78 ℃; Inert atmosphere;

2,3-dibromobenzene; With n-butyllithium; In tetrahydrofuran; at -78 ℃; Inert atmosphere;

DOI:10.1021/jo300910w

Reference yield: 42.0%

→ (2-bromophenyl)-dimethylphosphine borane (1383686-32-5)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 1h; Inert atmosphere;

With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 1h;

upstream raw materials:

dimethylphosphine-borane

2,3-dibromobenzene

Refernces

• 1、 Bayardon, Jerome,Laureano, Hugo,Diemer, Vincent,Dutartre, Mathieu,Das, Utpal,Rousselin, Yoann,Henry, Jean-Christophe,Colobert, Francoise,Leroux, Frederic R.,Juge, Sylvain. "Stereoselective synthesis of o-bromo (or iodo)aryl P-chirogenic phosphines based on aryne chemistry". experimental part. p. 5759 - 5769. Retrieved 2012/08/08.