Dichloro(1,10-phenanthroline)platinum(II)

Base Information

• Chemical Name: Dichloro(1,10-phenanthroline)platinum(II)
• CAS No.: 18432-95-6
• Molecular Formula: C12H8 Cl2 N2 Pt
• Molecular Weight: 446.195
• Mol file: 18432-95-6.mol

Synonyms:Dichloro(1,10-phenanthroline)platinum(II);18432-95-6;dichloroplatinum;1,10-phenanthroline;C12H8Cl2N2Pt;SCHEMBL691376;C12-H8-Cl2-N2-Pt;Dichloro(1,10-phenanthroline)platinum(II), >=95.0%;Platinum, dichloro(1,10-phenanthroline-N1,N10)-, (SP-4-2)- (9CI)

Chemical Property of Dichloro(1,10-phenanthroline)platinum(II)

Chemical Property:

• Vapor Pressure: 3.38E-05mmHg at 25°C
• Melting Point: >350 °C
• Boiling Point: 365.1°Cat760mmHg
• Flash Point: 164.8°C
• PSA: 25.78000
• Density: g/cm³
• LogP: 4.15950
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 444.971248
• Heavy Atom Count: 17
• Complexity: 185

Purity/Quality:

98%,99%, ^*data from raw suppliers

Dichloro(1,10-phenanthroline)platinum(II) ≥95.0% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC2=C(C3=C(C=CC=N3)C=C2)N=C1.Cl[Pt]Cl
• Uses: Reactant for:Mixed-metal complexes incorporating platinum and lanthanide centersSynthesis of platinum complexes containing a chelating di-fluoro-substituted thiourea ligandAdduct formation between ternary Pt(III)-amino acid- aromatic diimine complexes and flavin mononucleotideCatalyst for the selective synthesis of monoorganotin trihalides

Technology Process of Dichloro(1,10-phenanthroline)platinum(II)

There total 21 articles about Dichloro(1,10-phenanthroline)platinum(II) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.7%

1,10-Phenanthroline (66-71-7) + K2PtCl2 → dichloro(1,10-phenanthroline)platinum(II) (18432-95-6)

Guidance literature:

In water; dimethyl sulfoxide; at 20 - 80 ℃; for 5h;

Reference yield: 98.0%

potassium tetrachloroplatinate(II) (10025-99-7) + 1,10-Phenanthroline (66-71-7) → dichloro(1,10-phenanthroline)platinum(II) (18432-95-6)

Guidance literature:

With HCl; In hydrogenchloride; mixing of hot solns., stiring and heating 30 min (pptn.); filtration, washing (hot water, EtOH), drying (vac.); elem. anal.;

Reference yield: 97.7%

hydrogenchloride (7647-01-0,15364-23-5) + potassium tetrachloroplatinate(II) (10025-99-7) + 1,10-phenanthroline hydrate (5144-89-8) → dichloro(1,10-phenanthroline)platinum(II) (18432-95-6)

Guidance literature:

In water; elem. anal.;

DOI:10.1246/bcsj.71.1363

upstream raw materials:

hydrogenchloride

potassium tetrachloroplatinate(II)

1,10-phenanthroline hydrate

[(1,10-phenanthroline)PtI(C₆H₅)]

Refernces

• 1、 La Manna, Sara,Florio, Daniele,Iacobucci, Ilaria,Napolitano, Fabiana,De Benedictis, Ilaria,Malfitano, Anna Maria,Monti, Maria,Ravera, Mauro,Gabano, Elisabetta,Marasco, Daniela. "A comparative study of the effects of platinum (Ii) complexes on β-amyloid aggregation: Potential neurodrug applications". . p. 1 - 13. Retrieved 2021/03/18.
• 2、 Sun, Yanyan,Wei, Huaixin,Zhang, Qiang,Zhao, Xin. "Platinum(II) Complexes with 1,10-Phenanthroline and Hydrophilic Alkoxyacetate Ligands as Potential Antitumor Agents". . . Retrieved 2019/01/16.