Azidotrimethylsilane

Base Information Edit

Chemical Name:Azidotrimethylsilane
CAS No.:4648-54-8
Deprecated CAS:150059-64-6,135108-15-5
Molecular Formula:C3H9N3Si
Molecular Weight:115.21
Hs Code.:29310095
European Community (EC) Number:225-078-5
UNII:EM57JSM2Y9
DSSTox Substance ID:DTXSID3063542
Nikkaji Number:J80.870I
Wikipedia:Trimethylsilyl_azide
Wikidata:Q2875204
Mol file:4648-54-8.mol

Synonyms:azidotrimethylsilane;Me3SiN3;trimethylsilyl azide

Suppliers and Price of Azidotrimethylsilane

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Azidotrimethylsilane
10g
$ 340.00

TRC
Trimethylsilyl Azide
10g
$ 65.00

TCI Chemical
Trimethylsilyl Azide >95.0%(GC)
5g
$ 22.00

TCI Chemical
Trimethylsilyl Azide >95.0%(GC)
25g
$ 73.00

TCI Chemical
Trimethylsilyl Azide >95.0%(GC)
100g
$ 218.00

Sigma-Aldrich
Azidotrimethylsilane 95%
50g
$ 251.00

Sigma-Aldrich
Trimethylsilyl azide for synthesis. CAS 4648-54-8, EC Number 225-078-5, chemical formula (CH ) SiN ., for synthesis
8180260025
$ 113.00

Sigma-Aldrich
Trimethylsilyl azide for synthesis
25 mL
$ 108.22

Sigma-Aldrich
Azidotrimethylsilane 95%
10g
$ 86.50

Oakwood
Trimethylsilyl Azide 85%
25g
$ 75.00

Total 99 raw suppliers

Chemical Property of Azidotrimethylsilane Edit

Chemical Property:

Appearance/Colour:clear colorless to slightly yellow liquid
Melting Point:-95 °C
Refractive Index:n20/D 1.415(lit.)
Boiling Point:95-96 °C
Flash Point:6 °C
Density:0.876 g/mL at 20 °C
Storage Temp.:Refrigerator
Sensitive.:Moisture Sensitive
Solubility.:Miscible with toluene, dichloromethane, diethyl ether and most o
Water Solubility.:decomposes
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:115.056573834
Heavy Atom Count:7
Complexity:97.2

Purity/Quality:

99% ^*data from raw suppliers

Azidotrimethylsilane ^*data from reagent suppliers

Safty Information:

Pictogram(s): F, T, N
Hazard Codes:F,T,N
Statements: 11-23/24/25-50/53-29
Safety Statements: 16-36/37/39-45-8-57-36/37-29

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Chemical Classes:Metals -> Metalloid Compounds (Silicon)
Canonical SMILES:C[Si](C)(C)N=[N+]=[N-]
Physical properties bp 95–96°C; n20 D 1.416; d 0.868 g cm?3; fp23°C; IR νmax 2100 cm?1; 1H NMR (CDCl3) δ = 0.22.
Uses Many applications of TMSA in organic synthesis have been reported but only representative examples are described herein.Substitution Reactions.Benzyl,allyl,and substituted alkyl halides are converted to the corresponding azides in 60–100% yields via reactions with TMSA under neutral conditions in a nonaqueous solvent (eq 1).By using tin(IV) chloride as a catalyst, secondary and tertiary cyclic and polycyclic halides are similarly transformed into the corresponding azides in 50–92% yields (eq 1). Trimethylsilyl azide is used as an azidonation reagent for amines, amides, aldehydes and ketones. It is involved in the preparation of alfa- and beta-siloxy azides from carbonyl compounds and epoxides. It is also used in the preparation of heterocyclic compounds and also acts as an effective substitute for hydrazoic acid. Further, it is used in the Oseltamivir total synthesis. Versatile azidonation reagent for amines, amides, aldehydes, and ketones.

Technology Process of Azidotrimethylsilane

There total 13 articles about Azidotrimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.9%