Silane, (4-bromophenoxy)trimethyl-

Base Information

• Chemical Name: Silane, (4-bromophenoxy)trimethyl-
• CAS No.: 17878-44-3
• Molecular Formula: C9H13BrOSi
• Molecular Weight: 245.191
• Hs Code.: 2931900090
• European Community (EC) Number: 241-831-0
• NSC Number: 96824
• UNII: 83AG4X9EPE
• DSSTox Substance ID: DTXSID7066275
• Nikkaji Number: J47.098H
• Wikidata: Q63408753
• Mol file: 17878-44-3.mol

Synonyms:(4-Bromophenoxy)trimethylsilane;17878-44-3;Silane, (4-bromophenoxy)trimethyl-;(4-bromophenoxy)-trimethylsilane;4-Trimethylsilyloxybromobenzene;1-Bromo-4-(trimethylsiloxy)benzene;4-bromophenoxytrimethylsilane;83AG4X9EPE;Benzene, 1-bromo-4-((trimethylsilyl)oxy)-;(4-Bromophenoxy)(trimethyl)silane;EINECS 241-831-0;NSC 96824;NSC-96824;Benzene, 1-bromo-4-[(trimethylsilyl)oxy]-;NSC96824;1-bromo-4-[(trimethylsilyl)oxy]Benzene;C9H13BrOSi;UNII-83AG4X9EPE;p-Bromophenoxytrimethylsilane;4-Bromotrimethylsiloxybenzene;C9-H13-Br-O-Si;NCIOpen2_006153;p-bromophenyoxytrimethylsilane;p-bromophenoxytri-methylsilane;p-Trimethylsiloxy bromobenzene;4-Bromophenol, TMS derivative;SCHEMBL3894497;DTXSID7066275;4-(Trimethylsilyloxy)bromobenzene;4-bromophenyl trimethylsilyl ether;(4-bromo-phenoxy)-trimethyl-silane;4-Bromophenol, trimethylsilyl ether;MFCD00040713;AKOS015913458;1-BROMO-4-TRIMETHYLSILOXYBENZENE;SILANE,(4-BROMOPHENYL),TRIMETHYL;AS-44237;1-Bromo-4-(trimethylsiloxy)benzene, 98%;CS-0324138;FT-0708340;EN300-2190486;A881369;J-011401;Q63408753;1-Bromo-4-(trimethylsiloxy)benzene, purum, >=97.0% (GC)

Chemical Property of Silane, (4-bromophenoxy)trimethyl-

Chemical Property:

• Vapor Pressure: 0.216mmHg at 25°C
• Refractive Index: n20/D 1.515(lit.)
• Boiling Point: 215.5 °C at 760 mmHg
• Flash Point: 97.2 °C
• PSA: 9.23000
• Density: 1.236 g/cm³
• LogP: 3.66280
• Sensitive.: Moisture Sensitive
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 243.99190
• Heavy Atom Count: 12
• Complexity: 136

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-(Trimethylsilyloxy)bromobenzene 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C[Si](C)(C)OC1=CC=C(C=C1)Br

Technology Process of Silane, (4-bromophenoxy)trimethyl-

There total 13 articles about Silane, (4-bromophenoxy)trimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-bromo-phenol (106-41-2) + 1,1,1,3,3,3-hexamethyl-disilazane (999-97-3) → (4-bromophenoxy)trimethylsilane (17878-44-3)

Guidance literature:

With ammonium chloride; Reflux;

Reference yield: 99.0%

chloro-trimethyl-silane (75-77-4) + 4-bromo-phenol (106-41-2) → (4-bromophenoxy)trimethylsilane (17878-44-3)

Guidance literature:

With triethylamine; In toluene; at 20 ℃; for 21h; Inert atmosphere;

DOI:10.1002/chem.201100909

Reference yield: 99.0%

4-bromo-phenol (106-41-2) + trimethylsilyl formate (18243-21-5) → (4-bromophenoxy)trimethylsilane (17878-44-3)

Guidance literature:

With [Ru(κ¹-OAc)(κ²-OAc)(κ³-1,1,1-tris(diphenylphosphinomethyl)ethane)]; In acetonitrile; at 70 ℃; for 1h; Solvent; Reagent/catalyst; Catalytic behavior; Inert atmosphere; Schlenk technique; Sealed tube;

upstream raw materials:

chloro-trimethyl-silane

4-bromo-phenol

1-bromo-4-methoxy-benzene

trimethylsilyl iodide

Downstream raw materials:

trimethyl-(4-trimethylsilanyloxy-phenyl)-silane

dimethyl-bis-(4-trimethylsilanyloxy-phenyl)-silane

2,2-bis(4-hydroxyphenyl)methylenecyclohexane

4-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-phenol

Refernces

• 1、 Oladee, Razieh,Zareyee, Daryoush,Khalilzadeh, Mohammad A.. "KF/clinoptilolite NPs: An efficient and heterogeneous catalyst for chemoselective silylation of alcohols and phenols". . p. 731 - 737. Retrieved 2021/03/31.
• 2、 -. "Preparation method of hydroxyphenylboronic acid". Paragraph 0034-0036; 0038-0040. . Retrieved 2020/05/08.