1-METHYL-4-(METHYLSULFINYL)BENZENE

Base Information

• Chemical Name: 1-METHYL-4-(METHYLSULFINYL)BENZENE
• CAS No.: 934-72-5
• Molecular Formula: C8H10 O S
• Molecular Weight: 154.233
• Hs Code.: 29309099
• Mol file: 934-72-5.mol

Synonyms:Sulfoxide,methyl p-tolyl (6CI,7CI,8CI); (?à)-Methyl p-tolyl sulfoxide; (?à)-p-Tolyl methyl sulfoxide; 1-Methanesulfinyl-4-methylbenzene;1-Methyl-4-(methylsulfinyl)benzene; 4-(Methylsulfinyl)toluene; 4-Methylphenylmethyl sulfoxide; 4-Toluene methyl sulfoxide; Methyl 4-methylphenyl sulfoxide;Methyl 4-tolyl sulfoxide; Methyl p-methylphenyl sulfoxide; Methyl p-tolylsulfoxide; NSC 141186; p-Methylphenyl methyl sulfoxide; p-Tolyl methylsulfoxide

Chemical Property of 1-METHYL-4-(METHYLSULFINYL)BENZENE

Chemical Property:

• Melting Point: 44-46 °C(lit.)
• Refractive Index: 1.5780 (estimate)
• Boiling Point: 113-114 °C2 mm Hg(lit.)
• Flash Point: 124.6°C
• PSA: 36.28000
• Density: 1.15g/cm³
• LogP: 2.59810
• Solubility.: soluble in Methanol

Purity/Quality:

98%,99%, ^*data from raw suppliers

(R)-(+)-Methyl p-tolyl sulfoxide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Methyl p-tolyl sulfoxide may be used as a catalyst in the preparation of homoallylic alcohols by the allylation of aldehydes with allyltrichlorosilane. It may be used as a ligand in the synthesis of molybdenum chlorocomplexes.

Technology Process of 1-METHYL-4-(METHYLSULFINYL)BENZENE

There total 74 articles about 1-METHYL-4-(METHYLSULFINYL)BENZENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-methylphenyl methylsulfide (623-13-2) → Methyl p-tolyl sulfoxide (934-72-5)

Guidance literature:

With propan-1-ol; dihydrogen peroxide; In methanol; for 5h;

DOI:10.1055/s-1990-27059

Reference yield: 98.0%

S-methyl-S-(p-tolyl)sulfoximine (20414-85-1,22132-97-4,52720-03-3,121123-21-5) → Methyl p-tolyl sulfoxide (934-72-5)

Guidance literature:

With tert.-butylnitrite; In chloroform; at 25 ℃; for 0.25h;

Reference yield: 93.0%

4-methylphenyl methylsulfide (623-13-2) → Methyl p-tolyl sulfoxide (934-72-5) + Methyl p-tolyl sulfone (3185-99-7)

Guidance literature:

With chloro-trimethyl-silane; In acetonitrile; at -15 ℃; for 11h;

DOI:10.1016/S0040-4039(00)00828-5

upstream raw materials:

4-methylphenyl methylsulfide

dibromo-methyl-p-tolyl-λ⁴-sulfane

isoaalloxazine hydroperoxide

chloro-trimethyl-silane

Downstream raw materials:

dibromo-methyl-p-tolyl-λ⁴-sulfane

(R)-p-tolylsulfinylacetophenone

1-Cyclohexyl-2-((S)-toluene-4-sulfinyl)-ethanone

2-Adamantanone

Refernces

• 1、 Davidson, Stuart C.,Gomes, Gabriel dos Passos,Kuhn, Leah R.,Alabugin, Igor V.,Kennedy, Alan R.,Tomkinson, Nicholas C.O.. "Organocatalytic sulfoxidation". . . Retrieved 2020/12/07.
• 2、 Li, Jin-Heng,Li, Yang,Sun, Qing,Xue, Qi,Zhang, Ting-Ting. "Electrochemical oxygenation of sulfides with molecular oxygen or water: Switchable preparation of sulfoxides and sulfones". supporting information. p. 10314 - 10318. Retrieved 2021/12/17.