2-Bromo-4,6-dichloroaniline

Base Information

• Chemical Name: 2-Bromo-4,6-dichloroaniline
• CAS No.: 697-86-9
• Molecular Formula: C6H4BrCl2N
• Molecular Weight: 240.914
• Hs Code.: 29214200
• DSSTox Substance ID: DTXSID00373620
• Nikkaji Number: J347.092J
• Wikidata: Q72454076
• Mol file: 697-86-9.mol

Synonyms:2-Bromo-4,6-dichloroaniline;697-86-9;Benzenamine, 2-bromo-4,6-dichloro-;2-bromo-4,6-dichloro-aniline;6-bromo-2,4-dichloroaniline;2,4-Dichloro-6-bromoaniline;SCHEMBL3605101;DTXSID00373620;DTPADCOGQUOGHT-UHFFFAOYSA-N;Aniline, 2-bromo-4,6-dichloro-;AMY28453;CK1170;MFCD00040936;2-Bromo-4,6-dichloroaniline, 98%;AKOS005354418;AS-18846;B2197;CS-0097295;FT-0611431;EN300-185474;A836649;Z1269195667

Chemical Property of 2-Bromo-4,6-dichloroaniline

Chemical Property:

• Appearance/Colour: pinkish to light brown crystalline powder
• Vapor Pressure: 0.00588mmHg at 25°C
• Melting Point: 81-83 °C(lit.)
• Refractive Index: 1.648
• Boiling Point: 273 °C at 760 mmHg
• PKA: -0.05±0.10(Predicted)
• Flash Point: 121.8 °C
• PSA: 26.02000
• Density: 1.827 g/cm³
• LogP: 3.91930
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 238.89042
• Heavy Atom Count: 10
• Complexity: 122

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Bromo-4,6-dichloroaniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=C(C=C(C(=C1Cl)N)Br)Cl

Technology Process of 2-Bromo-4,6-dichloroaniline

There total 12 articles about 2-Bromo-4,6-dichloroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2,4-Dichloroaniline (554-00-7,51908-09-9) → 2,4-dichloro-6-bromoaniline (697-86-9)

Guidance literature:

With N-Bromosuccinimide; at 10 ℃; for 0.00666667h;

Reference yield:

N-(2,4-dichlorophenyl)acetamide (6975-29-7) → 2,4-dichloro-6-bromoaniline (697-86-9)

Guidance literature:

With acetic acid; Durch Bromierung;

Reference yield:

2-bromoaniline (615-36-1) → 2,4-dichloro-6-bromoaniline (697-86-9)

Guidance literature:

With hydrogenchloride; chlorine;

upstream raw materials:

chloroform

2-chloro-4,6-dibromoaniline

acetic acid-(2,4,N-trichloro-anilide)

N-(2,4-dichlorophenyl)acetamide

Downstream raw materials:

2-bromo-4,6-dichloro-N-nitro-aniline

1-bromo-3,5-dichlorobenzene

N-(2-bromo-4,6-dichlorophenyl)acetamide

bromine

Refernces

• 1、 Yang, Weijun,Zhou, Jun,Wang, Binjie,Ren, Hongjun. "Lewis acid-promoted synthesis of unsymmetrical and highly functionalized carbazoles and dibenzofurans from biaryl triazenes: Application for the total synthesis of clausine C, clausine R, and clauraila A". supporting information; scheme or table. p. 13665 - 13669. Retrieved 2012/01/15.
• 2、 Hanson, James R.,Saberi, Hamid. "The electrophilic substitution of some 2,4- and 2,6- dihaloacetanilides". . p. 699 - 701. Retrieved 2007/10/03.