Docosanamide

Base Information

• Chemical Name: Docosanamide
• CAS No.: 3061-75-4
• Molecular Formula: C22H45 N O
• Molecular Weight: 339.605
• Hs Code.: 29241990
• European Community (EC) Number: 221-304-1
• UNII: DI790A5561
• DSSTox Substance ID: DTXSID7062821
• Nikkaji Number: J106.783D
• Wikidata: Q27276408
• Metabolomics Workbench ID: 37321
• Mol file: 3061-75-4.mol

Synonyms:Docosanamide;Behenamide;3061-75-4;Behenic acid amide;Behenylamide;Behenic amide;Kemamide B;UNII-DI790A5561;EINECS 221-304-1;DI790A5561;EC 221-304-1;Docsoamide;Amide C22;LUTAMIDE BR;BEHENAMIDE [INCI];SCHEMBL49285;Behenamide, analytical standard;BEHENIC ACID AMIDE [MI];DTXSID7062821;CHEBI:165591;LMFA08010020;MFCD00047905;AKOS028108511;HY-W127445;MS-25178;CS-0185677;D1007;FT-0634629;E82293;J-018039;Q27276408;ERU

Chemical Property of Docosanamide

Chemical Property:

• Appearance/Colour: COA
• Vapor Pressure: 4.78E-09mmHg at 25°C
• Melting Point: 110-113 ºC
• Refractive Index: 1.46
• Boiling Point: 471.1°Cat760mmHg
• PKA: 16.61±0.40(Predicted)
• Flash Point: 100 ºC
• PSA: 43.09000
• Density: 0.865g/cm³
• LogP: 7.99390
• Storage Temp.: Room Temperature
• Solubility.: Dichloromethane (Slightly), Chloroform (Slightly, Heated), Methanol (Very Slight
• XLogP3: 9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 20
• Exact Mass: 339.350115059
• Heavy Atom Count: 24
• Complexity: 252

Purity/Quality:

99.9% ^*data from raw suppliers

Behenamide ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCCCCCCCC(=O)N
• Uses: Behenamide is a fatty acid amide as an angiogenic. The mechanism of angiogenic activity is unknown and this lipid does not promote proliferation of endothelial cells or induce inflammatory effects.

Technology Process of Docosanamide

There total 3 articles about Docosanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

n-docosanoic acid (112-85-6) → Docosanylamide (3061-75-4)

Guidance literature:

n-docosanoic acid; With oxalyl dichloride; In toluene; for 2h; Inert atmosphere; Reflux;

With ammonium hydroxide; In water;

DOI:10.1016/j.molliq.2020.112587

Reference yield:

docosanoyl chloride (21132-76-3) → Docosanylamide (3061-75-4)

Guidance literature:

With ammonia; In chloroform;

DOI:10.1021/j100151a035

Reference yield:

→ Docosanylamide (3061-75-4)

Guidance literature:

1.) Docosansaeure, Thionylchlorid am Rueckfluss, 2.) NH3 in Benzol;

upstream raw materials:

n-docosanoic acid

docosanoyl chloride

Downstream raw materials:

n-heneicosylammonium tosylate

1-aminodocosane

bis-docosanoylamino-methane

Refernces

• 1、 -. "Method and apparatus for manufacturing carboxylic acid amide compound". Paragraph 0059-0062; 0076. . Retrieved 2017/06/02.
• 2、 Weissbuch, I.,Majewski, J.,Kjaer, K.,Als-Nielsen, J.,Lahav, M.,Leiserowitz, L.. "Mixed Monolayers for the Design of Structured Surfaces To Induce Oriented 3-D Crystallization". . p. 12848 - 12857. Retrieved 2007/10/02.