1-Docosanamine

Base Information

• Chemical Name: 1-Docosanamine
• CAS No.: 14130-06-4
• Deprecated CAS: 457883-18-0
• Molecular Formula: C22H47 N
• Molecular Weight: 325.622
• Hs Code.: 2921199090
• European Community (EC) Number: 237-982-7
• DSSTox Substance ID: DTXSID6065713
• Nikkaji Number: J216.876F
• Wikidata: Q81992345
• Mol file: 14130-06-4.mol

Synonyms:docosan-1-amine;1-Docosanamine;14130-06-4;Docosylamine;EINECS 237-982-7;MFCD09923495;docosanylamine;n-docosyl-amine;SCHEMBL119115;DTXSID6065713;C22H47N;AC2249;AKOS027256604;CS-11704;SY028561;CS-0446186;A919774

Chemical Property of 1-Docosanamine

Chemical Property:

• Vapor Pressure: 1.79E-06mmHg at 25°C
• Melting Point: 63°C
• Refractive Index: 1.4649 (estimate)
• Boiling Point: 395.8°Cat760mmHg
• PKA: 10.67±0.10(Predicted)
• Flash Point: 182°C
• PSA: 26.02000
• Density: 0.823g/cm³
• LogP: 8.46730
• XLogP3: 10.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 20
• Exact Mass: 325.370850503
• Heavy Atom Count: 23
• Complexity: 190

Purity/Quality:

98%Min ^*data from raw suppliers

Docosan-1-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCCCCCCCCN

Technology Process of 1-Docosanamine

There total 9 articles about 1-Docosanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

N-docosylphthalimide (107513-47-3) → 1-aminodocosane (14130-06-4)

Guidance literature:

With methylamine; In methanol; at 80 ℃; for 16h; Schlenk technique;

DOI:10.1002/chem.201500707

Reference yield: 70.0%

1-azido-docosane (66143-74-6) → 1-aminodocosane (14130-06-4)

Guidance literature:

With hydrogen; palladium on activated charcoal; In hexane; at 20 ℃; for 3h; under 3206.4 Torr;

DOI:10.1021/jm061240d

Reference yield: 43.0%

Docosanylamide (3061-75-4) → 1-aminodocosane (14130-06-4)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 24h; Reflux;

DOI:10.1016/j.molliq.2020.112587

upstream raw materials:

N-docosylphthalimide

1-azido-docosane

1-Bromodocosane

1-docosanol

Downstream raw materials:

N-docosyl-3,4,5-tribenzyloxybenzamide

2-docosylamino-5-nitropyridine

Refernces

• 1、 Yokoyama, Soichi,Hirose, Takashi,Matsuda, Kenji. "Effects of Alkyl Chain Length and Hydrogen Bonds on the Cooperative Self-Assembly of 2-Thienyl-Type Diarylethenes at a Liquid/Highly Oriented Pyrolytic Graphite (HOPG) Interface". supporting information. p. 13569 - 13576. Retrieved 2015/09/22.
• 2、 Schott, Herbert,Haeussler, Markus P.,Schwendener, Reto A.. "Synthesis of 4-Alkylcytosine Nucleosides and Evaluation of Cytostatic Activity in the L1210 Murine Leukemia". . p. 465 - 470. Retrieved 2007/10/02.