4-AMINO-3,5-DINITROBENZOTRIFLUORIDE

Base Information

• Chemical Name: 4-AMINO-3,5-DINITROBENZOTRIFLUORIDE
• CAS No.: 445-66-9
• Molecular Formula: C7H4F3N3O4
• Molecular Weight: 251.122
• Hs Code.: 2921420090
• Mol file: 445-66-9.mol

Synonyms:p-Toluidine,a,a,a-trifluoro-2,6-dinitro- (7CI,8CI);2,6-Dinitro-4-(trifluoromethyl)aniline;2,6-Dinitro-4-(trifluoromethyl)benzenamine;4-Amino-3,5-dinitrobenzotrifluoride;

Chemical Property of 4-AMINO-3,5-DINITROBENZOTRIFLUORIDE

Chemical Property:

• Melting Point: 144-149 °C (lit.)
• Boiling Point: 313.1 °C at 760 mmHg
• Flash Point: 143.1 °C
• PSA: 117.66000
• Density: 1.686 g/cm³
• LogP: 3.73160

Purity/Quality:

98%min ^*data from raw suppliers

4-Amino-3,5-dinitrobenzotrifluoride 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-AMINO-3,5-DINITROBENZOTRIFLUORIDE

There total 5 articles about 4-AMINO-3,5-DINITROBENZOTRIFLUORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-chloro-3,5-dinitrobenzotrifluoride (393-75-9) → 2,6-dinitro-4-trifluoromethylaniline (445-66-9)

Guidance literature:

With ammonia;

Reference yield:

3,5-dinitrobenzotrifluoride (401-99-0) + N-butylamine (109-73-9,85404-21-3) → 2,6-dinitro-4-trifluoromethylaniline (445-66-9) + N-n-butyl-2,6-dinitro-4-(trifluoromethyl)aniline (10223-72-0)

Guidance literature:

With potassium tert-butylate; In N,N-dimethyl-formamide; at 13 ℃; Electrochemical reaction;

DOI:10.1002/1099-0690(20021)2002:2<251::aid-ejoc251>3.0.co;2-a

Reference yield:

2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)benzeneamine (1582-09-8,71281-30-6,75635-23-3,89300-31-2) → 3-nitro-5-trifluoromethyl-1,2-phenylenediamine (2078-01-5) + 2,6-dinitro-4-trifluoromethylaniline (445-66-9) + α,α,α-trifluoro-5-nitro-N4-propyltoluene-3,4-diamine (2078-02-6) + α,α,α-trifluoro-2,6-dinitro-N-propyl-p-toluidine (2077-99-8) + 2,6-dinitro-4-trifluoromethyl-2',6'-dinitro-4'-<(trifluoromethyl)azo>benzene (69145-34-2) + 2-ethyl-7-nitro-5-(trifluoromethyl)-1H-benzimidazole (51026-15-4)

Guidance literature:

In methanol; water; Mechanism; Irradiation;

DOI:10.1021/jf00055a017

upstream raw materials:

4-chloro-3,5-dinitrobenzotrifluoride

phenyl 2,6-dinitro-4-trifluoromethylphenyl ether

2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)benzeneamine

3,5-dinitrobenzotrifluoride

Downstream raw materials:

N,N-Dimethyl-N'-(2,6-dinitro-4-trifluoromethylphenyl)formamidine

4-(2,6-Dinitro-4-trifluoromethyl-phenylamino)-2,3,5,6-tetrafluoro-benzonitrile

3-nitro-5-trifluoromethyl-1,2-phenylenediamine

Refernces

• 1、 Mabury, Scott A.,Crosby, Donald G.. "19F NMR as an Analytical Tool for Fluorinated Agrochemical Research". . p. 1845 - 1848. Retrieved 2007/10/03.
• 2、 -. "Quinoxaline derivatives as immune regulants". . . Retrieved 2008/06/13.