Methyl picolinate

Base Information Edit

Chemical Name:Methyl picolinate
CAS No.:2459-07-6
Molecular Formula:C7H7NO2
Molecular Weight:137.138
Hs Code.:HYSICAL AND CHEMICAL PROPERTIES PHYSICAL STATE clear to slightly yellow liquid
European Community (EC) Number:219-545-2
NSC Number:1459
UNII:II4AAE7Y3A
DSSTox Substance ID:DTXSID4062432
Nikkaji Number:J27.977C
Wikidata:Q63398035
Metabolomics Workbench ID:93713
ChEMBL ID:CHEMBL309354
Mol file:2459-07-6.mol

Synonyms:Methyl picolinate;2459-07-6;Methyl pyridine-2-carboxylate;2-Picolinic acid methyl ester;2-Pyridinecarboxylic acid, methyl ester;Methyl 2-pyridinecarboxylate;Picolinic acid, methyl ester;methylpicolinate;2-Carbomethoxypyridine;Pyridine-2-carboxylic acid methyl ester;Picolinic Acid Methyl Ester;MFCD00038038;II4AAE7Y3A;2-Pyridinecarboxylic acid methyl ester;2-(Methoxycarbonyl)pyridine;NSC-1459;carbomethoxypyridine;Methyl picolinate, 99%;UNII-II4AAE7Y3A;METHYL-2-PICOLINATE;methylpyridine-2-carboxylate;SCHEMBL247011;CHEMBL309354;DTXSID4062432;NSC1459;pyridine-2-carboxylic acid methyl;CHEBI:167765;BCP25790;NSC 1459;3-methylpicolinate;EINECS 219-545-2;s6317;AKOS000567519;CS-W005458;GS-3031;5-ethyl-2,2-dimethylthiomorpholin-3-one;AC-22483;SY005022;AM20070160;FT-0628794;FT-0652587;P0423;EN300-49544;O11979;Q-101880;Q63398035;Z19673259;F0001-0835

Suppliers and Price of Methyl picolinate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
MethylPicolinate
5g
$ 60.00

TCI Chemical
Methyl Pyridine-2-carboxylate >98.0%(GC)
250g
$ 271.00

TCI Chemical
Methyl Pyridine-2-carboxylate >98.0%(GC)
25g
$ 45.00

Rieke Metals
Methylpicolinate 97%
2g
$ 723.00

Rieke Metals
Methylpicolinate 97%
5g
$ 1470.00

Rieke Metals
Methylpicolinate 97%
1g
$ 478.00

Matrix Scientific
Methyl picolinate 95+%
10g
$ 25.00

Matrix Scientific
Methyl picolinate 95+%
100g
$ 170.00

Frontier Specialty Chemicals
Methyl Pyridine-2-carboxylate 99%
25g
$ 158.00

Crysdot
Methylpicolinate 96%
100g
$ 137.00

Total 111 raw suppliers

Chemical Property of Methyl picolinate Edit

Chemical Property:

Appearance/Colour:clear to slightly yellow liquid
Vapor Pressure:0.0778mmHg at 25°C
Melting Point:18.7oC
Refractive Index:1.521
Boiling Point:227.4 °C at 760 mmHg
PKA:pK1:2.21(＋1) (25°C)
Flash Point:91.3 °C
PSA：39.19000
Density:1.137 g/cm³
LogP:0.86820
Storage Temp.:Inert atmosphere,Room Temperature
Water Solubility.:Slightly soluble in water.
XLogP3:0.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:137.047678466
Heavy Atom Count:10
Complexity:125

Purity/Quality:

98% Min ^*data from raw suppliers

MethylPicolinate ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC=CC=N1
Uses Methyl picolinate is used as pharmaceutical intermediate.

Technology Process of Methyl picolinate

There total 49 articles about Methyl picolinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 109-09-1
2-chloropyridine

: 67-56-1
methanol

: 201230-82-2
carbon monoxide

: 2459-07-6,260998-83-2
methyl pyridine-2-carboxylate

Guidance literature:: With dichloro[2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]palladium(II); triethylamine; at 100 ℃; for 5h; under 2585.74 Torr;
DOI:10.1021/ol0498287