potassium pyridine-2-carboxylate

Base Information

• Chemical Name: potassium pyridine-2-carboxylate
• CAS No.: 25108-36-5
• Molecular Formula: C6H5 N O2 . K
• Molecular Weight: 161.202
• Hs Code.: 2933399090
• Mol file: 25108-36-5.mol

Synonyms:2-Pyridinecarboxylicacid, potassium salt (9CI); Picolinic acid, potassium salt (8CI); Potassium2-pyridinecarboxylate; Potassium picolinate

Chemical Property of potassium pyridine-2-carboxylate

Chemical Property:

• Vapor Pressure: 0.000836mmHg at 25°C
• Boiling Point: 292.5°Cat760mmHg
• Flash Point: 130.7°C
• PSA: 53.02000
• Density: g/cm³
• LogP: -0.55490

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of potassium pyridine-2-carboxylate

There total 1 articles about potassium pyridine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2-Hydroxymethylpyridine (586-98-1) → potassium picolinate (25108-36-5)

Guidance literature:

With C₁₂H₁₄ClN₂Ru⁽¹⁺⁾*F₆P^(1-); potassium hydroxide; In toluene; at 110 ℃; for 6h; Inert atmosphere;

DOI:10.1021/acs.inorgchem.9b02691

Reference yield: 92.0%

1-bromo-octane (111-83-1) + potassium picolinate (25108-36-5) → octyl 2-pyridinecarboxylate (5335-69-3)

Guidance literature:

With Aliquat 336; at 85 ℃; for 24h;

Reference yield: 85.0%

W(CO)5(2-Mepy) (39210-59-8) + tetraphenylphosphonium bromide (2751-90-8) + potassium picolinate (25108-36-5) → {Ph4P}{W(2-pic)(CO)4}

Guidance literature:

In acetone; byproducts: CO; under oxygen free dry N2, equimolar amts., refluxing of W-compd. and K(2-pic) until CO evolution ceased (30-45 min), cooling at room temp., filtration, addn. of {Ph4P}Br, stirring for some min; addn. of diethylether, filtration, solidification on diln. of cold hexane, filtration, washing with hexane/diethylether, drying in vacuo, elem. anal.;

DOI:10.1016/0022-328X(88)80094-9

upstream raw materials:

2-Hydroxymethylpyridine

Downstream raw materials:

ethyl-2-picolinate

octyl 2-pyridinecarboxylate

picolinic acid

pyridine-2-carboxylic acid benzyl ester

Refernces

• 1、 Gunanathan, Chidambaram,Kishore, Jugal,Pattanaik, Sandip,Pradhan, Deepak Ranjan. "Cobalt-Catalyzed Acceptorless Dehydrogenation of Alcohols to Carboxylate Salts and Hydrogen". supporting information. . Retrieved 2020/03/03.
• 2、 Cherepakhin, Valeriy,Williams, Travis J.. "Iridium catalysts for acceptorless dehydrogenation of alcohols to carboxylic acids: Scope and mechanism". . p. 3754 - 3763. Retrieved 2018/05/23.