OCTYL PICOLINATE

Base Information

• Chemical Name: OCTYL PICOLINATE
• CAS No.: 5335-69-3
• Molecular Formula: C14H21NO2
• Molecular Weight: 235.326
• Hs Code.: 2933399090
• Mol file: 5335-69-3.mol

Synonyms:pyridine-2-carboxylic acid octyl ester;picolinic acid octyl ester;n-octyl picolinate;Pyridin-2-carbonsaeure-octylester;octyl 2-pyridinecarboxylate;Octyl picolinate;

Chemical Property of OCTYL PICOLINATE

Chemical Property:

• Vapor Pressure: 8.48E-05mmHg at 25°C
• Boiling Point: 340.7°C at 760 mmHg
• Flash Point: 159.8°C
• PSA: 39.19000
• Density: 0.996g/cm³
• LogP: 3.59890

Purity/Quality:

99% ^*data from raw suppliers

Octylpicolinate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of OCTYL PICOLINATE

There total 12 articles about OCTYL PICOLINATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-bromo-octane (111-83-1) + potassium picolinate (25108-36-5) → octyl 2-pyridinecarboxylate (5335-69-3)

Guidance literature:

With Aliquat 336; at 85 ℃; for 24h;

Reference yield: 89.0%

2-Cyanopyridine (100-70-9,1232006-36-8) + octanol (111-87-5) → pyridine-2-carboxylic acid amide (1452-77-3) + octyl 2-pyridinecarboxylate (5335-69-3)

Guidance literature:

With cerium(IV) oxide; water; In o-xylene; at 160 ℃; for 26h; Inert atmosphere;

DOI:10.1021/acscatal.6b00272

Reference yield: 82.0%

2-Picolinic acid (98-98-6) + octanol (111-87-5) → octyl 2-pyridinecarboxylate (5335-69-3)

Guidance literature:

2-Picolinic acid; With iodine; triphenylphosphine; In acetonitrile; at 25 - 85 ℃; for 0.25h; Microwave irradiation; Green chemistry;

octanol; In acetonitrile; at 85 ℃; for 0.616667h; chemoselective reaction; Microwave irradiation; Green chemistry;

DOI:10.1039/c6ra22558f

upstream raw materials:

2-Picolinic acid

octanol

2-picolinic acid hydrochloride

ethyl-2-picolinate

Downstream raw materials:

octanol

Refernces

• 1、 Hara, Naofumi,Uemura, Nao,Nakao, Yoshiaki. "C2-Selective silylation of pyridines by a rhodium-aluminum complex". supporting information. p. 5957 - 5960. Retrieved 2021/06/18.
• 2、 Rapeyko, Anastasia,Climent, Maria J.,Corma, Avelino,Concepción, Patricia,Iborra, Sara. "Nanocrystalline CeO2 as a Highly Active and Selective Catalyst for the Dehydration of Aldoximes to Nitriles and One-Pot Synthesis of Amides and Esters". . p. 4564 - 4575. Retrieved 2016/07/12.