Carmoterol

Base Information Edit

Chemical Name:Carmoterol
CAS No.:147568-66-9
Molecular Formula:C₂₁H₂₄N₂O₄
Molecular Weight:368.433
Hs Code.:
UNII:9810NUL4D1
DSSTox Substance ID:DTXSID201046374
Nikkaji Number:J423.240B
Wikipedia:Carmoterol
Wikidata:Q25104123
NCI Thesaurus Code:C171749
Pharos Ligand ID:7DCHD2KASWVB
ChEMBL ID:CHEMBL1094785
Mol file:147568-66-9.mol

Synonyms:carmoterol;carmoterol hydrochloride;CHF 4226.01;CHF4232.01;TA 2005;TA-2005

Suppliers and Price of Carmoterol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
8-Hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)quinolin-2(1H)-one 95+%
250 mg
$ 700.00

Matrix Scientific
Carmoterol
1g
$ 1679.00

Crysdot
8-Hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)quinolin-2(1H)-one 97%
100mg
$ 112.00

Crysdot
8-Hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)quinolin-2(1H)-one 97%
1g
$ 446.00

Crysdot
8-Hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)quinolin-2(1H)-one 97%
5g
$ 1340.00

Chemenu
2(1h)-quinolinone,8-hydroxy-5-[(1r)-1-hydroxy-2-[[(1r)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]- 97%
10g
$ 1650.00

Chemenu
2(1h)-quinolinone,8-hydroxy-5-[(1r)-1-hydroxy-2-[[(1r)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]- 97%
5g
$ 990.00

Chemenu
2(1h)-quinolinone,8-hydroxy-5-[(1r)-1-hydroxy-2-[[(1r)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]- 97%
1g
$ 330.00

American Custom Chemicals Corporation
CARMOTEROL 95.00%
1G
$ 2040.15

American Custom Chemicals Corporation
CARMOTEROL 95.00%
5MG
$ 498.01

Total 28 raw suppliers

Chemical Property of Carmoterol Edit

Chemical Property:

Vapor Pressure:5.71E-17mmHg at 25°C
Refractive Index:1.611
Boiling Point:634.487 °C at 760 mmHg
PKA:8.68±0.20(Predicted)
Flash Point:337.526 °C
PSA：94.58000
Density:1.247 g/cm³
LogP:3.19150
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:2.1
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:368.17360725
Heavy Atom Count:27
Complexity:518

Purity/Quality:

99% ^*data from raw suppliers

8-Hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)quinolin-2(1H)-one 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CC1=CC=C(C=C1)OC)NCC(C2=C3C=CC(=O)NC3=C(C=C2)O)O
Isomeric SMILES:C[C@H](CC1=CC=C(C=C1)OC)NC[C@@H](C2=C3C=CC(=O)NC3=C(C=C2)O)O
Recent ClinicalTrials:Dose Finding Study of CHF 4226 for Treating Patients With COPD
Recent EU Clinical Trials:EVALUATION OF THE EFFECT OF 4 WEEKS TREATMENT WITH CHF 4226 pMDI 2μg DOSE GIVEN ONCE DAILY IN THE EVENING ON 24-HOUR TROUGH FEV1 IN ADULT AND ADOLESCENT PATIENTS AGED 15 YEARS OR OVER WITH MODERATE OR SEVERE PERSISTANT ASTHMA. A MULTICENTER, DOUBLE-BLIND, DOUBLE-DUMMY, RANDOMISED, PARALLEL GROUP, PLACEBO AND ACTIVE (FORMOTEROL 12μg B.I.D.) CONTROLLED, EFFICACY, SAFETY AND TOLERABILITY STUDY.

Technology Process of Carmoterol

There total 2 articles about Carmoterol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: