Didodecylamine

Base Information

• Chemical Name: Didodecylamine
• CAS No.: 3007-31-6
• Molecular Formula: C24H51N
• Molecular Weight: 353.676
• Hs Code.: 2921199090
• European Community (EC) Number: 221-114-9
• NSC Number: 56451,16573
• UNII: 5KR2ML6H0C
• DSSTox Substance ID: DTXSID4062777
• Nikkaji Number: J80.612I
• Wikidata: Q27262492
• Mol file: 3007-31-6.mol

Synonyms:Didodecylamine;3007-31-6;Di-n-dodecylamine;1-Dodecanamine, N-dodecyl-;Dilaurylamine;N-dodecyldodecan-1-amine;N-dodecyl-1-dodecanamine;Alamine 204;N,N-Didodecylamine;UNII-5KR2ML6H0C;5KR2ML6H0C;EINECS 221-114-9;NSC 16573;NSC 56451;NSC-16573;NSC-56451;AI3-16576;dilauryl amine;N,N-Didodecylamine #;SCHEMBL64804;DTXSID4062777;Didodecylamine, >=97.0% (GC);NSC16573;NSC56451;MFCD00041918;AKOS015915202;AS-37823;BP-31196;CS-0204568;D0267;FT-0625180;Propanedioic acid, 2-amino-, 1,3-diethyl ester;A820176;J-660049;W-106959;Q27262492

Chemical Property of Didodecylamine

Chemical Property:

• Appearance/Colour: white crystalline solid
• Vapor Pressure: 1.78E-07mmHg at 25°C
• Melting Point: 45-47 °C
• Refractive Index: 1.451
• Boiling Point: 426.3 °C at 760 mmHg
• PKA: pK1:10.99(+1) (25°C)
• Flash Point: 200.3 °C
• PSA: 12.03000
• Density: 0.815 g/cm³
• LogP: 8.80870
• Storage Temp.: 2-8°C
• XLogP3: 11
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 22
• Exact Mass: 353.402150631
• Heavy Atom Count: 25
• Complexity: 192

Purity/Quality:

98%,99%, ^*data from raw suppliers

Didodecylamine >97.0%(T) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCNCCCCCCCCCCCC
• Description: Didodecylamine is a secondary amine. It is reported as standard amine enhancer and its dermal enhancement properties has been studied using in vitro diffusion cell techniques. Solidification point of dodecylamine has been reported to be 26.2°C.
• Uses: Didodecylamine may be used:to promote the crystal growth of 2D nanosheets of GdOCl with approximately square cross sections to investigate the effect of alkyl chain length of amine on phase transfer of aqueous synthesized gold nanoparticles (AuNPs) from water to toluenein the preparation of novel class of liquid crystalline complexes, by the interaction of copper nitrate

Technology Process of Didodecylamine

There total 64 articles about Didodecylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

n-Dodecylamine (124-22-1) → N,N-didodecylamine (3007-31-6) + tridodecylamine (102-87-4)

Guidance literature:

With Co₂Rh₂/C; In toluene; at 180 ℃; for 6h; under 760.051 Torr; Temperature; Time; Solvent; Autoclave; Inert atmosphere;

DOI:10.1002/adsc.201701522

Reference yield: 84.0%

undecyl cyanide (2437-25-4) → N,N-didodecylamine (3007-31-6) + tridodecylamine (102-87-4)

Guidance literature:

With hydrogen; silica gel; copper; at 160 ℃; for 2.69444h; under 33002.6 Torr; Product distribution; Rate constant; other temperatures, other catalysts;

Reference yield: 75.8%

undecyl cyanide (2437-25-4) → n-Dodecylamine (124-22-1) + N,N-didodecylamine (3007-31-6)

Guidance literature:

With hydrogen; In methanol; at 80 ℃; for 4h; under 37503.8 Torr; Reagent/catalyst; Catalytic behavior; Autoclave;

upstream raw materials:

n-Dodecylamine

lauric acid amide

1-Iodododecane

methyl n-dodecanoate

Downstream raw materials:

N-methyldidodecylamine

tridodecylamine

Refernces

• 1、 Thongbamrer, Chopaka,Roobsoong, Wanlapa,Sattabongkot, Jetsumon,Opanasopit, Praneet,Yingyongnarongkul, Boon-ek. "Serum Compatible Spermine-Based Cationic Lipids with Nonidentical Hydrocarbon Tails Mediate High Transfection Efficiency". . . Retrieved 2022/02/03.
• 2、 Coeck, Robin,De Vos, Dirk E.. "One-pot reductive amination of carboxylic acids: a sustainable method for primary amine synthesis". supporting information. p. 5105 - 5114. Retrieved 2020/08/25.