ethyl N-[(benzyloxy)carbonyl]glycyl-O-ethyl-3-oxoserinate

Base Information Edit

Chemical Name:ethyl N-[(benzyloxy)carbonyl]glycyl-O-ethyl-3-oxoserinate
CAS No.:14769-29-0
Molecular Formula:C17H22 N2 O7
Molecular Weight:366.371
Hs Code.:
Mol file:14769-29-0.mol

Synonyms:Malonicacid, [2-(carboxyamino)acetamido]-, N-benzyl diethyl ester (6CI,8CI); Serine,O-ethyl-3-oxo-N-[N-[(phenylmethoxy)carbonyl]glycyl]-, ethyl ester; NSC 13400

Suppliers and Price of ethyl N-[(benzyloxy)carbonyl]glycyl-O-ethyl-3-oxoserinate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of ethyl N-[(benzyloxy)carbonyl]glycyl-O-ethyl-3-oxoserinate Edit

Chemical Property:

Vapor Pressure:1.55E-11mmHg at 25°C
Boiling Point:535.4°Cat760mmHg
Flash Point:277.6°C
Density:1.236g/cm³

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of ethyl N-[(benzyloxy)carbonyl]glycyl-O-ethyl-3-oxoserinate

There total 4 articles about ethyl N-[(benzyloxy)carbonyl]glycyl-O-ethyl-3-oxoserinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 13433-00-6
diethyl aminomalonate hydrochloride

: 1138-80-3
N-(Benzyloxycarbonyl)glycine

: 14769-29-0
diethyl 2-[[2-(benzyloxycarbonylamino)acetyl]amino]propanedioate

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; at 20 ℃;
DOI:10.1002/cbdv.201200261

Reference yield:

: 6829-40-9
aminomalonic acid diethyl ester

: 15050-24-5
N-(benzyloxycarbonyl)glycyl chloride

: 14769-29-0
diethyl 2-[[2-(benzyloxycarbonylamino)acetyl]amino]propanedioate

Guidance literature:: With diethyl ether;
DOI:10.1557/JMR.2002.0375

Reference yield:

: 1138-80-3
N-(Benzyloxycarbonyl)glycine

: 14769-29-0
diethyl 2-[[2-(benzyloxycarbonylamino)acetyl]amino]propanedioate

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 5 h / 20 °C

2: triethylamine / dichloromethane / 0.33 h / 0 - 20 °C / Reflux

With oxalyl dichloride; triethylamine; N,N-dimethyl-formamide; In dichloromethane;