Pentafluorophenyl formate

Base Information

• Chemical Name: Pentafluorophenyl formate
• CAS No.: 111333-97-2
• Molecular Formula: C7HF5O2
• Molecular Weight: 212.076
• Mol file: 111333-97-2.mol

Synonyms:formic acid pentafluorophenyl ester;Phenol,pentafluoro-,formate;pentafluorophenyl formate;

Chemical Property of Pentafluorophenyl formate

Chemical Property:

• Refractive Index: 1.4240 (25℃)
• PSA: 57.53000
• LogP: 2.42440

Purity/Quality:

99% ^*data from raw suppliers

Pentafluorophenylformate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Pentafluorophenyl formate

There total 3 articles about Pentafluorophenyl formate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

formic acid (64-18-6) + 2,3,4,5,6-pentafluorophenol (771-61-9) → formic acid pentafluorophenyl ester (111333-97-2)

Guidance literature:

With dicyclohexyl-carbodiimide; In chloroform; at 0 ℃; for 1.5h;

DOI:10.1055/s-1987-27987

Reference yield:

m-nitrophenyl formate (1988-17-6) + pentafluorophenolate anion (26910-95-2) → 3-nitrophenolate anion (16554-54-4) + formic acid pentafluorophenyl ester (111333-97-2)

Guidance literature:

With potassium chloride; In water; at 25 ℃; Rate constant;

DOI:10.1021/ja00058a006

Reference yield:

(4-nitrophenyl) formate (1865-01-6) + pentafluorophenolate anion (26910-95-2) → formic acid pentafluorophenyl ester (111333-97-2) + p-nitrophenolate (14609-74-6)

Guidance literature:

With potassium chloride; In water; at 25 ℃; Rate constant;

DOI:10.1021/ja00058a006

upstream raw materials:

formic acid

2,3,4,5,6-pentafluorophenol

m-nitrophenyl formate

pentafluorophenolate anion

Downstream raw materials:

(3R,4R)-4-Benzyloxycarbonyloxy-3-((S)-2-formyl-2,3,4,9-tetrahydro-1H-β-carbolin-1-ylmethyl)-2-[1-methoxy-meth-(E)-ylidene]-hexanoic acid methyl ester

(3R,4R)-4-Benzyloxycarbonyloxy-3-((R)-2-formyl-2,3,4,9-tetrahydro-1H-β-carbolin-1-ylmethyl)-2-[1-methoxy-meth-(E)-ylidene]-hexanoic acid methyl ester

C₂₃H₂₃F₆N₃O₃

N-benzylformamide

Refernces

• 1、 Stefanidis, Dimitrios,Cho, Sayeon,Dhe-Paganon, Sirano,Jencks, William P.. "Structure-reactivity correlations for reactions of substituted phenolate anions with acetate and formate esters". . p. 1650 - 1656. Retrieved 2007/10/02.