2-NITROPHENYL PENTYL ETHER

Base Information

• Chemical Name: 2-NITROPHENYL PENTYL ETHER
• CAS No.: 39645-91-5
• Molecular Formula: C11H15 N O3
• Molecular Weight: 209.245
• Hs Code.: 2909309090
• Mol file: 39645-91-5.mol

Synonyms:2-Nitrophenylpentyl ether; NSC 28597; o-Nitrophenyl pentyl ether

Chemical Property of 2-NITROPHENYL PENTYL ETHER

Chemical Property:

• Vapor Pressure: 0.000824mmHg at 25°C
• Refractive Index: n20/D 1.522
• Boiling Point: 315.1°Cat760mmHg
• Flash Point: 131.7°C
• PSA: 55.05000
• Density: 1.093g/cm³
• LogP: 3.68700

Purity/Quality:

99.90% ^*data from raw suppliers

2-Nitrophenyl pentyl ether Selectophore ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 38
• Safety Statements: 37

MSDS Files:

Total 1 MSDS from other Authors

Useful:

Technology Process of 2-NITROPHENYL PENTYL ETHER

There total 5 articles about 2-NITROPHENYL PENTYL ETHER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

amyl iodide (628-17-1) + 2-hydroxynitrobenzene (88-75-5,78813-12-4) → 1-nitro-2-(pentyloxy)benzene (39645-91-5)

Guidance literature:

With potassium carbonate; In acetone; for 20h; Reflux; Inert atmosphere;

DOI:10.1021/jm200476p

Reference yield: 83.0%

pentan-1-ol (71-41-0) + 2-Nitroanisole (91-23-6) → 1-nitro-2-(pentyloxy)benzene (39645-91-5)

Guidance literature:

pentan-1-ol; With potassium tert-butylate; In 5,5-dimethyl-1,3-cyclohexadiene; at 80 ℃; Inert atmosphere;

2-Nitroanisole; With 2-phenyl-4,4,5,5-tetramethyl-1,3,2-dioxoborole; In 5,5-dimethyl-1,3-cyclohexadiene; at 80 ℃; for 12h; Reagent/catalyst; Temperature; Inert atmosphere;

DOI:10.1002/ejoc.201901779

Reference yield:

1-Bromopentane (110-53-2) + 2-hydroxynitrobenzene (88-75-5,78813-12-4) → 1-nitro-2-(pentyloxy)benzene (39645-91-5)

Guidance literature:

With potassium carbonate; xylene;

DOI:10.1021/ja01312a017

upstream raw materials:

amyl iodide

silver(I) 2-nitrophenoxide

1-Bromopentane

2-hydroxynitrobenzene

Downstream raw materials:

diethyl 2-((2-(pentyloxy)phenylamino)methylene)malonate

(2-iodo-phenyl)-pentyl ether

6-Oxo-2-(2-pentyloxy-phenylamino)-1,6-dihydro-pyrimidine-5-carboxylic acid ethyl ester

6-Oxo-2-(2-pentyloxy-phenylamino)-1,6-dihydro-pyrimidine-5-carboxylic acid

Refernces

• 1、 Pasquini, Serena,De Rosa, Maria,Pedani, Valentina,Mugnaini, Claudia,Guida, Francesca,Luongo, Livio,De Chiaro, Maria,Maione, Sabatino,Dragoni, Stefania,Frosini, Maria,Ligresti, Alessia,Di Marzo, Vincenzo,Corelli, Federico. "Investigations on the 4-quinolone-3-carboxylic acid motif. 4. Identification of new potent and selective ligands for the cannabinoid type 2 receptor with diverse substitution patterns and antihyperalgesic effects in mice". supporting information; experimental part. p. 5444 - 5453. Retrieved 2011/09/30.