4-(1H-pyrrol-1-yl)benzohydrazide

Base Information

• Chemical Name: 4-(1H-pyrrol-1-yl)benzohydrazide
• CAS No.: 112575-84-5
• Molecular Formula: C11H11N3O
• Molecular Weight: 201.228
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID90397517
• Wikidata: Q82198939
• ChEMBL ID: CHEMBL353046
• Mol file: 112575-84-5.mol

Synonyms:4-(1H-pyrrol-1-yl)benzohydrazide;112575-84-5;4-pyrrol-1-ylbenzohydrazide;Oprea1_404001;CHEMBL353046;SCHEMBL6580760;DTXSID90397517;BBL015546;MFCD02194575;STK032650;AKOS000285746;SB62224;CS-0270805;FT-0739997;EN300-228336

Chemical Property of 4-(1H-pyrrol-1-yl)benzohydrazide

Chemical Property:

• PSA: 60.05000
• Density: 1.24g/cm3
• LogP: 2.17200
• XLogP3: 1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 201.090211983
• Heavy Atom Count: 15
• Complexity: 218

Purity/Quality:

98%min ^*data from raw suppliers

4-(1H-Pyrrol-1-yl)benzohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CN(C=C1)C2=CC=C(C=C2)C(=O)NN

Technology Process of 4-(1H-pyrrol-1-yl)benzohydrazide

There total 7 articles about 4-(1H-pyrrol-1-yl)benzohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

1-(4-(methyl carboxylate) phenyl) pyrrole (23351-08-8) → 4-(1H-pyrrol-1-yl)benzoic acid hydrazide (112575-84-5)

Guidance literature:

With hydrazine hydrate; In methanol; at 85 ℃;

DOI:10.1016/j.jcat.2021.08.020

Reference yield: 77.0%

1-(4-ethoxycarbonylphenyl)pyrrole (5044-37-1) → 4-(1H-pyrrol-1-yl)benzoic acid hydrazide (112575-84-5)

Guidance literature:

With hydrazine hydrate; In ethanol; for 3h;

DOI:10.1021/jm00399a021

Reference yield:

4-(1H-pyrrole-1-yl)benzoic acid (22106-33-8) → 4-(1H-pyrrol-1-yl)benzoic acid hydrazide (112575-84-5)

Guidance literature:

upstream raw materials:

1-(4-ethoxycarbonylphenyl)pyrrole

4-(1H-pyrrole-1-yl)benzoic acid

4-amino-benzoic acid

p-aminoethylbenzoate

Downstream raw materials:

N-(1,3-dioxoisoindolin-2-yl)-4-(1H-pyrrol-1-yl)benzamide

Refernces

• 1、 Balasubramaniam, Bhuvaneshwari,Dhara, Partha,Gupta, Raju K.,Kundu, Sabuj,Panja, Dibyajyoti,Sau, Anirban. "Utilization of caffeine carbon supported cobalt catalyst in the tandem synthesis of pyrroles from nitroarenes and alkenyl diols". . p. 244 - 254. Retrieved 2021/09/07.
• 2、 Joshi, Shrinivas D.,Kumar, Devendra,Dixit, Sheshagiri R.,Tigadi, Nageshwar,More, Uttam A.,Lherbet, Christian,Aminabhavi, Tejraj M.,Yang, Kap Seung. "Synthesis, characterization and antitubercular activities of novel pyrrolyl hydrazones and their Cu-complexes". . p. 21 - 39. Retrieved 2016/08/19.