3-bromo-5-isopropoxybenzenamine

Base Information

• Chemical Name: 3-bromo-5-isopropoxybenzenamine
• CAS No.: 112930-36-6
• Molecular Formula: C9H12BrN
• Molecular Weight: 214.105
• Mol file: 112930-36-6.mol

Synonyms:3-Bromo-5-Isopropylaniline;

Chemical Property of 3-bromo-5-isopropoxybenzenamine

Chemical Property:

• PSA: 26.02000
• LogP: 3.73590

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-bromo-5-isopropoxybenzenamine

There total 4 articles about 3-bromo-5-isopropoxybenzenamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

t-butyl N-(3-bromo-5-isopropylphenyl)carbamate (112930-40-2) → 3-bromo-5-isopropylaniline (112930-36-6)

Guidance literature:

With hydrogenchloride; In ethanol; for 2h; Heating;

Reference yield:

3-bromo-5-isopropylbenzoic acid (112930-39-9) → 3-bromo-5-isopropylaniline (112930-36-6)

Guidance literature:

Multi-step reaction with 3 steps

1: thionyl chloride / 5 h / Heating

2: 1.) sodium azide (20percent) / 1.) acetone, from 0 deg C to RT, 10 min, 2.) reflux, 5 h

3: 100 percent / hydrochloric acid (3M) / ethanol / 2 h / Heating

With hydrogenchloride; thionyl chloride; sodium azide; In ethanol;

Reference yield:

C9H10Br2Mg → 3-bromo-5-isopropylaniline (112930-36-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 1.) magnesium, iodine, 2.) hydrochloric acid (3M) / 1.) ether, reflux, 2.) ether, overnight

2: thionyl chloride / 5 h / Heating

3: 1.) sodium azide (20percent) / 1.) acetone, from 0 deg C to RT, 10 min, 2.) reflux, 5 h

4: 100 percent / hydrochloric acid (3M) / ethanol / 2 h / Heating

With hydrogenchloride; thionyl chloride; sodium azide; iodine; magnesium; In ethanol;

upstream raw materials:

t-butyl N-(3-bromo-5-isopropylphenyl)carbamate

3-bromo-5-isopropylbenzoic acid

3-bromo-5-isopropyl-benzoyl chloride

Downstream raw materials:

(biphenyl-2'-yl)(3-fluoro-5-isopropylphenyl)methanone

(E,Z)-1-(biphenyl-2'-yl)-1-(3-fluoro-5-isopropylphenyl)buta-1,3-diene

α-(3'-fluoro-5'-isopropylphenyl)biphenyl-2-methanol

1-(biphenyl-2'-yl)-1-(3-fluoro-5-isopropylphenyl)but-3-en-1-ol

Refernces