2,4-DIMETHYLVALERONITRILE

Base Information

• Chemical Name: 2,4-DIMETHYLVALERONITRILE
• CAS No.: 6339-13-5
• Molecular Formula: C6H11 N
• Molecular Weight: 97.16
• Mol file: 6339-13-5.mol

Synonyms:Pentenenitrile,2-methyl- (5CI); Valeronitrile, 2-methyl- (6CI,7CI,8CI); 2-Cyanopentane;2-Methylpentanenitrile; 2-Methylvaleronitrile; NSC 38217

Chemical Property of 2,4-DIMETHYLVALERONITRILE

Chemical Property:

• Vapor Pressure: 3.89mmHg at 25°C
• Melting Point: -32.8°C (estimate)
• Refractive Index: 1.3979
• Boiling Point: 150.2°C at 760 mmHg
• Flash Point: 46°C
• PSA: 23.79000
• Density: 0.8g/cm³
• LogP: 1.94618

Purity/Quality:

99% ^*data from raw suppliers

2-METHYLPENTANENITRILE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,4-DIMETHYLVALERONITRILE

There total 12 articles about 2,4-DIMETHYLVALERONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

N,N-Dimethyl-N'-[2-methyl-pent-(E)-ylidene]-hydrazine → 2-methyl-Pentanenitrile (6339-13-5)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; for 2h;

DOI:10.1002/prac.19943360516

Reference yield: 85.0%

2-methylvaleraldehyde (123-15-9) → 2-methyl-Pentanenitrile (6339-13-5)

Guidance literature:

With hydroxylamine hydrochloride; sodium iodide; In acetonitrile; for 1.5h; Heating;

DOI:10.1055/s-2003-41408

Reference yield: 51.0%

2-bromopentane (107-81-3) → 2-methyl-Pentanenitrile (6339-13-5)

Guidance literature:

With cyanide^(1-);

-(CH2)3-⁺PBu3; In water; at 110 ℃; for 5.5h;

DOI:10.1021/jo01302a035

upstream raw materials:

2-methylpentanamide

propyl bromide

propiononitrile

1-iodo-propane

Downstream raw materials:

2-methylpentanamide

Refernces

• 1、 Rojas, Giovanni,Baughman, Travis W.,Wagener, Kenneth B.. "Quantitative α-alkylation of primary nitriles". . p. 3923 - 3931. Retrieved 2008/03/14.
• 2、 Giurg,Mlochowski,Ambrozak. "Hydrogen peroxide oxidation of N,N-dimethylhydrazones promoted by selenium compounds, titanosilicalites or acetonitrile". . p. 1713 - 1720. Retrieved 2007/10/03.