Guanidine, N,N'-bis(1-methylethyl)-N''-phenyl-

Base Information

• Chemical Name: Guanidine, N,N'-bis(1-methylethyl)-N''-phenyl-
• CAS No.: 13134-19-5
• Molecular Formula: C13H21N3
• Molecular Weight: 219.33
• Mol file: 13134-19-5.mol

Synonyms:

Chemical Property of Guanidine, N,N'-bis(1-methylethyl)-N''-phenyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Guanidine, N,N'-bis(1-methylethyl)-N''-phenyl-

There total 8 articles about Guanidine, N,N'-bis(1-methylethyl)-N''-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

aniline (62-53-3) + diisopropyl-carbodiimide (693-13-0) → 1,3-diisopropyl-2-phenylguanidine (13134-19-5)

Guidance literature:

With zinc trifluoromethanesulfonate; In benzene-d6; at 80 ℃; for 3h; In air; Sealed tube;

DOI:10.1039/b923249b

Reference yield: 99.0%

aniline (62-53-3) + diisopropyl-carbodiimide (693-13-0) → N-phenyl- N',N''-diisopropylguanidine (13134-19-5)

Guidance literature:

With C₂₄H₅₀N₅Si₂Y; In neat (no solvent); at 20 ℃; for 2h; Inert atmosphere; Schlenk technique;

DOI:10.1021/acs.organomet.0c00606

Reference yield: 91.0%

N-((methylsulfonyl)oxy)benzimidoyl chloride (5023-82-5) + isopropylamine (75-31-0) → 1,3-diisopropyl-2-phenylguanidine (13134-19-5)

Guidance literature:

N-((methylsulfonyl)oxy)benzimidoyl chloride; isopropylamine; With N,N,N,N,-tetramethylethylenediamine; In tetrahydrofuran; at 20 ℃;

isopropylamine; In tetrahydrofuran; at 50 ℃;

DOI:10.1016/j.tetlet.2009.07.147

upstream raw materials:

aniline

diisopropyl-carbodiimide

N,N', N''-tri(isopropyl)guanidine

N′,N″-diisopropyl-N,N-dimethyl guanidine

Downstream raw materials:

C₃₄H₅₆CaN₆O₂

C₁₅H₁₉N₃O₂

Refernces

• 1、 Batrice, Rami J.,Eisen, Moris S.. "Catalytic insertion of E-H bonds (E = C, N, P, S) into heterocumulenes by amido-actinide complexes". . p. 939 - 944. Retrieved 2016.
• 2、 Li, Bangyu,Wang, Yaorong,Yao, Yingming,Zhang, Yong,Shen, Qi. "Synthesis, structure and reactivity of samarium complexes supported by Schiff-base ligands". . p. 2409 - 2414. Retrieved 2009.
• 3、 Tong, Hongbo,Yu, Dehui,Zhou, Meisu. "Syntheses, crystal structures and catalytic property of two bulky tin(II) complexes". . . Retrieved 2020.
• 4、 Li, Qinghai,Wang, Shaowu,Zhou, Shuangliu,Yang, Gaosheng,Zhu, Xiancui,Liu, Yuyu. "Highly atom efficient guanylation of both aromatic and secondary amines catalyzed by simple lanthanide amides". . p. 6763 - 6767. Retrieved 2007.
• 5、 Song, Qiuhong,Tong, Hongbo,Zhou, Meisu. "Five-coordination aluminum complexes: Synthesis, crystal structures and utilization for the construction of substituted guanidines". . . Retrieved 2021/12/23.
• 6、 Yu, Lu,Wang, Fenhua,Wang, Hui,Wang, Shaoyin,Wu, Yunjun,Gu, Xiaoxia. "Synthesis, structure and catalytic activity of rare-earth metal amino complexes incorporating imino-functionalized indolyl ligand". . . Retrieved 2021/01/05.