(2-Oxooxolan-3-yl)azanium;bromide

Base Information

• Chemical Name: (2-Oxooxolan-3-yl)azanium;bromide
• CAS No.: 6305-38-0
• Molecular Formula: C4H8BrNO2
• Molecular Weight: 182.017
• Hs Code.: 29322985
• Mol file: 6305-38-0.mol

Synonyms:(2-oxooxolan-3-yl)azanium;bromide

Chemical Property of (2-Oxooxolan-3-yl)azanium;bromide

Chemical Property:

• Appearance/Colour: white to light beige crystalline powder
• Melting Point: 220-225 °C(lit.)
• Boiling Point: 257.1 °C at 760 mmHg
• Flash Point: 120.1 °C
• PSA: 52.32000
• LogP: 0.91900
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Water Solubility.: almost transparency
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 180.97384
• Heavy Atom Count: 8
• Complexity: 91.7

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-Aminodihydrofuran-2(3H)-oneHydrobromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COC(=O)C1[NH3+].[Br-]

Technology Process of (2-Oxooxolan-3-yl)azanium;bromide

There total 5 articles about (2-Oxooxolan-3-yl)azanium;bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

L-methionine (63-68-3,26062-47-5,58576-49-1) → (S)-(-)-α-amino-γ-butyrolactone hydrobromide (6305-38-0,15295-77-9,67580-93-2,110045-70-0)

Guidance literature:

With bromoacetic acid; In water; acetic acid; isopropyl alcohol; Reflux; Inert atmosphere;

DOI:10.1039/c2ob27155a

Reference yield: 81.0%

DL-Homoserine (1927-25-9,119736-88-8) → α-amino-γ-butyrolactone hydrobromide (6305-38-0)

Guidance literature:

With hydrogen bromide; Reflux;

Reference yield: 78.0%

α-bromo-γ-butyrolactone (5061-21-2) → α-amino-γ-butyrolactone hydrobromide (6305-38-0)

Guidance literature:

α-bromo-γ-butyrolactone; With ammonium hydroxide; at 0 ℃; for 6h;

With barium dihydroxide; In water; at 85 ℃; for 4h;

With sulfuric acid; In water;

upstream raw materials:

L-methionine

bromoacetic acid

(S)-methioninol

DL-Homoserine

Downstream raw materials:

3-benzoylamino-dihydro-furan-2-one

α-(1,3-dibenzylhexahydro-2-oxo-1,3,5-triazin-5-yl)-γ-butyrolactone

(+/-)-N-hexanoyl-homoserine lactone

Refernces

• 1、 Wu, Guangqi,Ge, Chenglong,Liu, Xingyi,Wang, Shuo,Wang, Letian,Yin, Lichen,Lu, Hua. "Synthesis of water soluble and multi-responsive selenopolypeptides via ring-opening polymerization of N-carboxyanhydrides". supporting information. p. 7860 - 7863. Retrieved 2019/07/12.
• 2、 -. "A cogeneration process for producing sulfur and sulfur on behalf of acetate acid diester method (by machine translation)". Paragraph 0081; 0083. . Retrieved 2018/12/02.