Technology Process of Pentanoic acid,
4-[(3-chlorobenzoyl)amino]-5-[(2-ethylhexyl)amino]-5-oxo-
There total 4 articles about Pentanoic acid,
4-[(3-chlorobenzoyl)amino]-5-[(2-ethylhexyl)amino]-5-oxo- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) triethylamine, ethyl chloroformate / 1.) THF, -10 deg C, 15 min, 2.)a) THF, -10 deg C, 1 h, b) RT, 3 h
2: H2, H2O / 10percent Pd/activated charcoal / methanol / 2 h / 760 Torr / Ambient temperature
3: aq. NaOH / tetrahydrofuran / 3 h / Ambient temperature
With
sodium hydroxide; water; hydrogen; chloroformic acid ethyl ester; triethylamine;
palladium on activated charcoal;
In
tetrahydrofuran; methanol;
DOI:10.1021/jm00079a003
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) triethylamine, ethyl chloroformate / 1.) THF, -10 deg C, 15 min, 2.)a) THF, -10 deg C, 1 h, b) RT, 3 h
2: H2, H2O / 10percent Pd/activated charcoal / methanol / 2 h / 760 Torr / Ambient temperature
3: aq. NaOH / tetrahydrofuran / 3 h / Ambient temperature
With
sodium hydroxide; water; hydrogen; chloroformic acid ethyl ester; triethylamine;
palladium on activated charcoal;
In
tetrahydrofuran; methanol;
DOI:10.1021/jm00079a003
- Guidance literature:
-
Multi-step reaction with 2 steps
1: H2, H2O / 10percent Pd/activated charcoal / methanol / 2 h / 760 Torr / Ambient temperature
2: aq. NaOH / tetrahydrofuran / 3 h / Ambient temperature
With
sodium hydroxide; water; hydrogen;
palladium on activated charcoal;
In
tetrahydrofuran; methanol;
DOI:10.1021/jm00079a003
