(tert-Butyl)phenylphosphinic acid

Base Information

• Chemical Name: (tert-Butyl)phenylphosphinic acid
• CAS No.: 4923-86-8
• Molecular Formula: C10H15O2P
• Molecular Weight: 198.202
• Mol file: 4923-86-8.mol

Synonyms:tert-Butylphenylphosphinic acid;Phosphinic acid,tert-butylphenyl;

Chemical Property of (tert-Butyl)phenylphosphinic acid

Chemical Property:

• Vapor Pressure: 2.31E-06mmHg at 25°C
• Melting Point: 156-157 °C(Solv: water (7732-18-5))
• Boiling Point: 377.3°Cat760mmHg
• PKA: 3.01±0.50(Predicted)
• Flash Point: 182°C
• PSA: 47.11000
• Density: 1.1g/cm³
• LogP: 2.38080

Purity/Quality:

99% ^*data from raw suppliers

TERT-BUTYL PHENYL PHOSPHINIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (tert-Butyl)phenylphosphinic acid

There total 23 articles about (tert-Butyl)phenylphosphinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.5%

tert-butylphenylphosphinic acid chloride (4923-85-7) → t-butyl(phenyl)phosphinic acid (4923-86-8)

Guidance literature:

With potassium hydroxide; In ethanol; water; Heating;

Reference yield: 86.0%

tert-Butylphenylphosphine oxide (98976-30-8,57956-51-1,6057-79-0,82945-11-7) → t-butyl(phenyl)phosphinic acid (4923-86-8)

Guidance literature:

With Oxone; In methanol; water; at 20 ℃; for 24h;

DOI:10.1021/jacs.9b07340

Reference yield: 82.0%

t-butyl phenyl phosphinic trifluoroacetate (169783-28-2) → t-butyl(phenyl)phosphinic acid (4923-86-8)

Guidance literature:

With methanol; for 0.25h;

upstream raw materials:

tert-Butylphenylphosphine oxide

tertiary butyl chloride

Dichlorophenylphosphine

tert-butylphenylphosphinic acid chloride

Downstream raw materials:

tert-butylphenylphosphinic 4-methylbenzenesulfonic anhydride

tert-butyl(phenyl)phosphonic acid bromide

diisopropylphosphate

tert-Butyl(phenyl)phosphinsaeurefluorid

Refernces

• 1、 Nycz. "New aspects connected with the synthesis of H-phosphinate anhydrides". experimental part. p. 589 - 594. Retrieved 2009/12/26.
• 2、 Goldeman, Waldemar,Olszewski, Tomasz K.,Boduszek, Bogdan,Sawka-Dobrowolska, Wanda. "Aminophosphine oxides in a pyridine series. Studies on the cleavage of pyridine-2- and pyridine-4-yl-(N-benzylamino)-methyldiphenylphosphine oxides in acidic solutions". . p. 4506 - 4518. Retrieved 2007/10/03.