p-(Dimethylamino)benzaldehyde oxime

Base Information

• Chemical Name: p-(Dimethylamino)benzaldehyde oxime
• CAS No.: 2929-84-2
• Molecular Formula: C₉H₁₂N₂O
• Molecular Weight: 164.207
• European Community (EC) Number: 622-595-1
• NSC Number: 522103
• DSSTox Substance ID: DTXSID80425919
• ChEMBL ID: CHEMBL498513
• Mol file: 2929-84-2.mol

Synonyms:p-(Dimethylamino)benzaldehyde oxime;37961-71-0;2929-84-2;4-Dimethylaminobenzaldoxim;4-[(HYDROXYIMINO)METHYL]-N,N-DIMETHYLANILINE;(E)-4-(Dimethylamino)benzaldehyde oxime;Benzaldehyde, p-(dimethylamino)-, oxime;(NE)-N-[[4-(dimethylamino)phenyl]methylidene]hydroxylamine;Benzaldehyde, 4-(dimethylamino)-, oxime;4-(Dimethylamino)benzaldehyde oxime;starbld0002175;MLS000772364;CHEMBL498513;SCHEMBL5384609;4-N,N-Dimethylaminobenzaldioxime;4-(N,Ndimethylamino)benzaldoxime;DTXSID80425919;UJYKADYTQMVUAG-JXMROGBWSA-N;MFCD00016413;NSC522103;STK325336;4-N,N-Dimethylaminobenzaldehyde oxime;AKOS001078432;MS-8781;NSC-522103;SMR000344546;CS-0336011;EN300-15679;4-[(E)-(hydroxyimino)methyl]-N,N-dimethylaniline;4-[(1E)-(hydroxyimino)methyl]-N,N-dimethylaniline;(4-((HYDROXYIMINO)METHYL)PHENYL)DIMETHYLAMINE;Z49568328

Chemical Property of p-(Dimethylamino)benzaldehyde oxime

Chemical Property:

• Vapor Pressure: 0.00233mmHg at 25°C
• Boiling Point: 276.4°Cat760mmHg
• Flash Point: 120.9°C
• PSA: 35.83000
• Density: 1.02g/cm³
• LogP: 1.56070
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 164.094963011
• Heavy Atom Count: 12
• Complexity: 149

Purity/Quality:

99% ^*data from raw suppliers

4-(N,N-Dimethylamino)benzaldoxime ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)C1=CC=C(C=C1)C=NO
• Isomeric SMILES: CN(C)C1=CC=C(C=C1)/C=N/O

Technology Process of p-(Dimethylamino)benzaldehyde oxime

There total 20 articles about p-(Dimethylamino)benzaldehyde oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-dimethylamino-benzaldehyde (100-10-7) → 4-dimethylaminobenzaldehyde oxime (2929-84-2,37961-71-0,77145-76-7)

Guidance literature:

With hydroxylamine hydrochloride; sodium acetate; In acetonitrile; for 4h; Reflux;

DOI:10.3184/174751917X15005550651302

Reference yield: 96.0%

N,N-dimethyl-4-hydroxymethylaniline (1703-46-4) → 4-dimethylaminobenzaldehyde oxime (2929-84-2,37961-71-0,77145-76-7)

Guidance literature:

N,N-dimethyl-4-hydroxymethylaniline; With dihydrogen peroxide; at 20 ℃; for 0.166667h; Green chemistry;

With hydroxylamine hydrochloride; for 3.2h; Catalytic behavior; Green chemistry;

DOI:10.1016/j.molstruc.2019.03.008

Reference yield: 93.0%

4-dimethylamino-benzaldehyde (100-10-7) → (E)-4-dimethylaminobenzaldehyde oxime (2929-84-2,37961-71-0,77145-76-7)

Guidance literature:

With 3 A molecular sieve; hydroxylamine hydrochloride; at 20 ℃; for 0.25h;

upstream raw materials:

4-dimethylamino-4'-(N,N-dimethylamino)benzylideneaniline

4-dimethylamino-benzaldehyde-(O-benzoyl oxime )

4-dimethylamino-benzaldehyde

hydroxylamine

Downstream raw materials:

4-dimethylamino-benzaldehyde-[O-(2,4-dinitro-phenyl)-oxime ]

C₂₀H₂₈N₄O₂Si

C₁₆H₁₈N₄O

4-Dimethylamino-O-p-tolyloxycarbimidoyl-benzaldoxim

Refernces

• 1、 Malpica,Calzadilla,Cordova,Torres,Saulny. "Kinetics and mechanism for oxime formation from 4-dimethylaminobenzaldehyde and 4-trimethylammoniobenzaldehyde iodide". . p. 387 - 392. Retrieved 1999.
• 2、 Chen, Ching-Chin,Chen, Yung-Chung,Graff, Bernadette,Hammoud, Fatima,Hijazi, Akram,Huang, Tung-Liang,Lalevée, Jacques,Lee, Zhong-Han. "Effect of the Steric Hindrance and Branched Substituents on Visible Phenylamine Oxime Ester Photoinitiators: Photopolymerization Kinetics Investigation through Photo-DSC Experiments". . . Retrieved 2021/11/04.
• 3、 Aarjane, Mohammed,Slassi, Siham,Tazi, Bouchra,Amine, Amina. "Synthesis and biological evaluation of novel isoxazole derivatives from acridone". . . Retrieved 2020/12/07.