1-PHENYL-2-PROPYLMETHANESULPHONATE

Base Information

• Chemical Name: 1-PHENYL-2-PROPYLMETHANESULPHONATE
• CAS No.: 61380-47-0
• Molecular Formula: C10H14 O3 S
• Molecular Weight: 214.285
• Hs Code.: 2906299090
• Mol file: 61380-47-0.mol

Synonyms:Benzeneethanol,a-methyl-, methanesulfonate (9CI);1-Phenyl-2-propyl mesylate;1-Phenyl-2-propyl methanesulfonate;a-Methylphenethyl methanesulfonate;

Chemical Property of 1-PHENYL-2-PROPYLMETHANESULPHONATE

Chemical Property:

• Vapor Pressure: 4.29E-05mmHg at 25°C
• Refractive Index: 1.521
• Boiling Point: 361.5°C at 760 mmHg
• Flash Point: 172.4°C
• PSA: 51.75000
• Density: 1.17g/cm³
• LogP: 2.67460

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-PHENYL-2-PROPYLMETHANESULPHONATE

There total 4 articles about 1-PHENYL-2-PROPYLMETHANESULPHONATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

3-phenyl-2-propanol (698-87-3,14898-87-4) + methanesulfonyl chloride (124-63-0) → (±)-1-phenylpropanyl-2-yl methansulfonate (61380-47-0)

Guidance literature:

With pyridine; at 20 ℃;

DOI:10.1055/s-0032-1317473 DOI:10.1055/s-0032-1317473

Reference yield: 86.0%

2-phenylethanol (60-12-8) + methanesulfonyl chloride (124-63-0) → (±)-1-phenylpropanyl-2-yl methansulfonate (61380-47-0)

Guidance literature:

With pyridine; at 20 ℃;

DOI:10.1055/s-0032-1317473 DOI:10.1055/s-0032-1317473

Reference yield:

2-fluoro-1-phenylpropane (40888-89-9) + trimethylsilyl methanesulfonate (10090-05-8) → (±)-1-phenylpropanyl-2-yl methansulfonate (61380-47-0)

Guidance literature:

With tris(pentafluorophenyl)borate; In 1,2-dichloro-ethane; at 20 ℃; for 0.0833333h; Glovebox; Schlenk technique;

DOI:10.1002/chem.201806272

upstream raw materials:

3-phenyl-2-propanol

methanesulfonyl chloride

2-phenylethanol

2-fluoro-1-phenylpropane

Downstream raw materials:

phenylpropane

amphetamine hydrochloride

1-phenylpropene

(2-bromopropyl)-benzene

Refernces

• 1、 Lenstra, Danny C.,Lenting, Peter E.,Mecinovi?, Jasmin. "Sustainable organophosphorus-catalysed Staudinger reduction". supporting information. p. 4418 - 4422. Retrieved 2018/10/17.
• 2、 Liu, Yajun,Xu, Yongnan,Jung, Sun Ho,Chae, Junghyun. "A facile and green protocol for nucleophilic substitution reactions of sulfonate esters by recyclable ionic liquids [bmim][X]". supporting information. p. 2692 - 2698,7. Retrieved 2012/12/12.