3-Pyridineacetic acid, a-(phenylmethylene)-, (E)-

Base Information

• Chemical Name: 3-Pyridineacetic acid, a-(phenylmethylene)-, (E)-
• CAS No.: 141694-17-9
• Molecular Formula: C₁₄H₁₁NO₂
• Molecular Weight: 225.247
• Mol file: 141694-17-9.mol

Synonyms:

Chemical Property of 3-Pyridineacetic acid, a-(phenylmethylene)-, (E)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Pyridineacetic acid, a-(phenylmethylene)-, (E)-

There total 5 articles about 3-Pyridineacetic acid, a-(phenylmethylene)-, (E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3t-phenyl-2-[3]pyridyl-acrylic acid methyl ester → α-(3-pyridyl)-cinnamic acid (141694-17-9)

Guidance literature:

With potassium hydroxide;

Reference yield:

methyl-3-pyridylketone (350-03-8) → α-(3-pyridyl)-cinnamic acid (141694-17-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 4>2S; sulfur / 170 °C / Erwaermen des Reaktionsprodukts in Methanol unter Einleiten von HCl

2: sodium; diethyl ether

3: methanol. KOH

With diammonium sulfide; potassium hydroxide; diethyl ether; sodium; sulfur;

Reference yield:

methyl pyridine-3-acetate (39998-25-9) → α-(3-pyridyl)-cinnamic acid (141694-17-9)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium; diethyl ether

2: methanol. KOH

With potassium hydroxide; diethyl ether; sodium;

upstream raw materials:

pyridyl-3-yl-acetic acid

benzaldehyde

methyl-3-pyridylketone

methyl pyridine-3-acetate

Downstream raw materials:

(E)-3-(2-phenylvinyl)pyridine

2-(1-oxy-[3]pyridyl)-3-phenyl-acrylic acid