Hexafluoroglutaric anhydride

Base Information

• Chemical Name: Hexafluoroglutaric anhydride
• CAS No.: 376-68-1
• Molecular Formula: C5F6 O3
• Molecular Weight: 222.044
• Hs Code.: 29171900
• European Community (EC) Number: 206-811-8
• DSSTox Substance ID: DTXSID90191037
• Nikkaji Number: J213.592B
• Wikidata: Q81985536
• Mol file: 376-68-1.mol

Synonyms:Hexafluoroglutaric anhydride;376-68-1;Perfluoroglutaric anhydride;3,3,4,4,5,5-Hexafluorodihydro-2H-pyran-2,6(3H)-dione;C5F6O3;3,3,4,4,5,5-hexafluorooxane-2,6-dione;2,2,3,3,4,4-Hexafluoropentanedioic Anhydride;EINECS 206-811-8;Hexafluoroglutaric acid anhydride;hexafluorooxane-2,6-dione;SCHEMBL316973;DTXSID90191037;Hexafluoroglutaric anhydride, 97%;C5-F6-O3;MFCD00006680;AKOS009099982;4-CHLORO-4-NITRODIPHENYLSULFIDE;AT23280;PS-10626;FT-0626997;H0745;EN300-25323

Chemical Property of Hexafluoroglutaric anhydride

Chemical Property:

• Appearance/Colour: Clear colorless to pale yellow liquid
• Vapor Pressure: 87.5mmHg at 25°C
• Refractive Index: n20/D 1.324(lit.)
• Boiling Point: 79.9°Cat760mmHg
• Flash Point: 3.3°C
• PSA: 43.37000
• Density: 1.76g/cm³
• LogP: 0.97570
• Sensitive.: Moisture Sensitive
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 0
• Exact Mass: 221.97516283
• Heavy Atom Count: 14
• Complexity: 281

Purity/Quality:

98%,99%, ^*data from raw suppliers

Hexafluoroglutaric anhydride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi,C
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Other Classes -> Acid Anhydrides, Other
• Canonical SMILES: C1(=O)C(C(C(C(=O)O1)(F)F)(F)F)(F)F

Technology Process of Hexafluoroglutaric anhydride

There total 5 articles about Hexafluoroglutaric anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,2-dichloro-3,3,4,4,5,5-hexafluorocyclopentene (706-79-6) → hexafluoropentanedioyl dichloride (678-77-3) + hexafluoroglutaric anhydride (376-68-1)

Guidance literature:

1,2-dichloro-3,3,4,4,5,5-hexafluorocyclopentene; With potassium permanganate; sodium hydroxide; pH=9;

With 1H-imidazole; oxalyl dichloride; 18-crown-6 ether; In dichloromethane; at 25 ℃; for 2.5h;

Reference yield:

hexafluoroglutaric acid (376-73-8) → hexafluoroglutaric anhydride (376-68-1)

Guidance literature:

With trichlorophosphate; at 150 ℃;

DOI:10.1021/ja01136a010

Reference yield:

hexafluoroglutaric acid (376-73-8) → hexafluoro-dihydro-furan-2-one (702-35-2) + hexafluoroglutaric anhydride (376-68-1)

Guidance literature:

at 230 - 260 ℃; Reaktion Dinatrium-Salzes der Hexafluorglutarsaeure_.Pyrolysis;

DOI:10.1021/ja01512a025

upstream raw materials:

hexafluoroglutaric acid

hexafluoropentanedioyl dichloride

1,2-dichloro-3,3,4,4,5,5-hexafluorocyclopentene

Downstream raw materials:

hexafluoroglutaric acid

Refernces

• 1、 -. "Preparation method of fluorine-containing carboxylic acid". Paragraph 0037-0038. . Retrieved 2020/07/12.