Technology Process of 2-Piperidinone,
1-methyl-6-[2-[2-(methylsulfonyl)-10H-phenothiazin-10-yl]ethyl]-
There total 6 articles about 2-Piperidinone,
1-methyl-6-[2-[2-(methylsulfonyl)-10H-phenothiazin-10-yl]ethyl]- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 93 percent / thionyl chloride / CHCl3 / 2 h / Heating
2: 93 percent / pyridine / 1 h / Ambient temperature
3: 78 percent / 10percent aqueous sodium metaperiodate / ruthenium(IV) oxide / ethyl acetate / 4 h / Ambient temperature
4: 66 percent / basic aluminum oxide / hexane; ethyl acetate / Ambient temperature
5: 87 percent / sodium hydride / dimethylformamide / Ambient temperature
6: 72 percent / sodium hydride / toluene / 22 h / Heating
With
pyridine; aluminum oxide; sodium periodate; thionyl chloride; sodium hydride;
ruthenium(IV) oxide;
In
hexane; chloroform; ethyl acetate; N,N-dimethyl-formamide; toluene;
DOI:10.1002/jhet.5570280202
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 93 percent / pyridine / 1 h / Ambient temperature
2: 78 percent / 10percent aqueous sodium metaperiodate / ruthenium(IV) oxide / ethyl acetate / 4 h / Ambient temperature
3: 66 percent / basic aluminum oxide / hexane; ethyl acetate / Ambient temperature
4: 87 percent / sodium hydride / dimethylformamide / Ambient temperature
5: 72 percent / sodium hydride / toluene / 22 h / Heating
With
pyridine; aluminum oxide; sodium periodate; sodium hydride;
ruthenium(IV) oxide;
In
hexane; ethyl acetate; N,N-dimethyl-formamide; toluene;
DOI:10.1002/jhet.5570280202
