PORPHINE

Base Information

• Chemical Name: PORPHINE
• CAS No.: 101-60-0
• Molecular Formula: C20H14N4
• Molecular Weight: 310.358
• Mol file: 101-60-0.mol

Synonyms:Porphine(6CI,7CI,8CI);21,22,23,24-Tetraazapentacyclo[16.2.1.13,6.18,11.113,16]tetracosa-1,3,5,7,9,11(23),12,14,16,18(21),19-undecaene;Porphin;Porphyrin;

Chemical Property of PORPHINE

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 360°C
• Refractive Index: 1.72
• Boiling Point: 804.4 °C at 760 mmHg
• Flash Point: 377.479 °C
• PSA: 56.30000
• Density: 1.353 g/cm³
• LogP: 1.19220
• Storage Temp.: −20°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

PORPHINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: Porphine (also called porphin) is a planar aromatic heterocyclic compound with a 12-carbon outside ring and four embedded pyrrole rings. It is a dark red crystalline solid that is soluble in some polar solvents such as pyridine and dioxane. It can be heated to 360 oC without melting. Porphine is the parent compound of a family of biologically and chemically relevant compounds called porphyrins. The potential of these compounds is enormous and it would be advantageous to use the porphine (porphyrin) unit as a building block for the synthesis of diverse porphyrin complexes with a wide range of applications.

Technology Process of PORPHINE

There total 83 articles about PORPHINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

4-(4-((tritylamino)methyl)phenoxy)phthalonitrile → porphyrin (101-60-0)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In n-heptan1ol;

DOI:10.1016/j.dyepig.2014.11.002

Reference yield: 77.0%

5,10,15,20-tetrakis(n-hexyloxycarbonyl)porphyrin → porphyrin (101-60-0)

Guidance literature:

With sulfuric acid; water; sodium sulfate; at 180 ℃; for 0.5h;

DOI:10.1016/j.tetlet.2006.10.010

Reference yield: 74.0%

meso-5,10,15,20-tetrakis(tert-butyl)porphyrin → porphyrin (101-60-0)

Guidance literature:

With sulfuric acid; at 90 ℃; for 0.25h;

DOI:10.1016/S0040-4039(01)02324-3

upstream raw materials:

2-pyrrole aldehyde

formic acid

ethanol

3-ethyl-4-methyl-1H-pyrrole

Downstream raw materials:

tetrakis(pentafluorophenyl)porphyrin

tetrakis(4-aminophenyl)porphyrin

Refernces

• 1、 Chen, Xianglan,Li, Yejing,Wang, Ao,Zhou, Lin,Lu, Shan,Zhou, Jiahong,Lin, Yun,Wei, Shaohua. "Protonation salt derivative with heavy-atom effect on phthalocyanine for enhanced in vitro photodynamic therapy". . p. 93 - 104. Retrieved 2015.
• 2、 Hodgson,Baker. "-". . p. 29,30,31. Retrieved 1967.
• 3、 Dogutan, Dilek Kiper,Ptaszek, Marcin,Lindsey, Jonathan S.. "Direct synthesis of magnesium porphine via 1-formyldipyrromethane". . p. 5008 - 5011. Retrieved 2007.
• 4、 Saltsman, Irena,Goldberg, Israel,Balasz, Yael,Gross, Zeev. "Porphine and pyrrole-substituted porphyrin from cyclocondensation of tripyrrane with mono-substituted pyrroles". . p. 239 - 244. Retrieved 2007.
• 5、 Liu, Peng Peng,Feng, Ya Qing,Gu, Cheng Zhi,Meng, Shu Xian,Zhang, Bao. "The facile synthesis of 5-formylporphyrin". . p. 505 - 508. Retrieved 2012.
• 6、 Rothemund. "-". . . Retrieved 1939.
• 7、 Dicker et al.. "-". . p. 560. Retrieved 1967.
• 8、 Zakavi, Saeed,Omidyan, Reza,Talebzadeh, Sadegh. "The influence of protonation on the structure and spectral properties of porphine: UV-vis, 1H NMR and: Ab initio studies". . p. 82219 - 82226. Retrieved 2016/09/09.