Silane, (cyclohexylcarbonyl)dimethylphenyl-

Base Information

• Chemical Name: Silane, (cyclohexylcarbonyl)dimethylphenyl-
• CAS No.: 150614-90-7
• Molecular Formula: C15H22OSi
• Molecular Weight: 246.425
• Mol file: 150614-90-7.mol

Synonyms:

Chemical Property of Silane, (cyclohexylcarbonyl)dimethylphenyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Silane, (cyclohexylcarbonyl)dimethylphenyl-

There total 15 articles about Silane, (cyclohexylcarbonyl)dimethylphenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

carbon monoxide (201230-82-2) + Cyclohexyl iodide (626-62-0) + dimethylphenyl(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)silane (185990-03-8) → (dimethyl(phenyl)silyl)(cyclohexyl)methanone (150614-90-7)

Guidance literature:

With chloro[1,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene]copper(I); sodium phenoxide; In 1,4-dioxane; at 60 ℃; for 12h; under 4560.31 Torr; Glovebox;

DOI:10.1021/jacs.9b12043

Reference yield: 87.0%

S-phenyl cyclohexanecarbothioate (58587-03-4) + (dimethyl(phenyl)silyl)zinc chloride (1234935-78-4) → (dimethyl(phenyl)silyl)(cyclohexyl)methanone (150614-90-7)

Guidance literature:

With bis(dibenzylideneacetone)-palladium⁽⁰⁾; tricyclohexylphosphine; In tetrahydrofuran; diethyl ether; at 20 ℃;

DOI:10.1246/cl.2011.959

Reference yield: 82.0%

cyclohexanecarboxylic acid anhydride (22651-87-2) + dimethylphenyl(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)silane (185990-03-8) → (dimethyl(phenyl)silyl)(cyclohexyl)methanone (150614-90-7)

Guidance literature:

With CuF(PPh₃)3; tetrabutylammonium triphenyldifluorosilicate; In toluene; at 20 ℃; for 6h; Inert atmosphere; Schlenk technique; Sealed tube;

DOI:10.1002/adsc.201300621

upstream raw materials:

N,N-dimethylcyclohexanecarboxamide

dimethyl(phenyl)silyllithium

1,1-biscyclohexanemethanol

cyclohexanylcarbonyl chloride

Downstream raw materials:

(E)-cyclohexyl dimethylphenylsilyl thioketone S-oxide

1-cyclohexyl-3-buten-1-ol

1-cyclohexyl-1-[dimethyl(phenyl)silyl]but-3-en-1-ol

cyclohexyl dimethylphenylsilyl thioketone

Refernces

• 1、 Feng, Jian-Jun,Oestreich, Martin. "Tertiary α-Silyl Alcohols by Diastereoselective Coupling of 1,3-Dienes and Acylsilanes Initiated by Enantioselective Copper-Catalyzed Borylation". supporting information. p. 8211 - 8215. Retrieved 2019/05/27.
• 2、 Cirriez, Virginie,Rasson, Corentin,Riant, Olivier. "Synthesis of acylsilanes by copper(I)-catalyzed addition of silicon nucleophiles onto acid derivatives". . p. 3137 - 3140. Retrieved 2013/12/04.