Benzenesulfonic acid, 3-nitro-, oxiranylmethyl ester

Base Information

• Chemical Name: Benzenesulfonic acid, 3-nitro-, oxiranylmethyl ester
• CAS No.: 152333-94-3
• Molecular Formula: C9H9NO6S
• Molecular Weight: 259.24
• Mol file: 152333-94-3.mol

Synonyms:

Chemical Property of Benzenesulfonic acid, 3-nitro-, oxiranylmethyl ester

Chemical Property:

Purity/Quality:

99.9% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenesulfonic acid, 3-nitro-, oxiranylmethyl ester

There total 2 articles about Benzenesulfonic acid, 3-nitro-, oxiranylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

oxiranyl-methanol (556-52-5) + 3-nitrobenzenesulphonyl chloride (121-51-7) → glycidyl nosylate (152333-94-3)

Guidance literature:

With triethylamine; In toluene; at -20 - -10 ℃; for 20h; Inert atmosphere;

DOI:10.3762/bjoc.9.154

Reference yield: 97.0%

3-nitrobenzenesulphonyl chloride (121-51-7) + (R)-oxiranemethanol (57044-25-4) → glycidyl nosylate (152333-94-3)

Guidance literature:

With triethanolamine;

Reference yield: 97.0%

glycidyl nosylate (152333-94-3) + 1-(3,4-dichloro)phenylpiperazine (57260-67-0) → 3[4-(3',4'-dichlorophenyl)piperazinyl]-1,2-epoxypropane (335165-60-1)

Guidance literature:

upstream raw materials:

oxiranyl-methanol

3-nitrobenzenesulphonyl chloride

(R)-oxiranemethanol

Downstream raw materials:

C₉H₉NO₄

benzyl-4-(2,3-epoxypropyl)-piperazine

1-(diphenylmethyl)-4-(2,3-epoxypropyl)piperazine

3-Nitrobenzenesulfonic acid

Refernces

• 1、 -. "TRICYCLIC COMPOUNDS FOR USE IN TREATMENT OF PROLIFERATIVE DISORDERS". Paragraph 00158; 00161; 00164; 00168; 00171; 00173; 00176. . Retrieved 2018/10/19.
• 2、 -. "METHODS OF MAKING COMPOUNDS HAVING A BETA-ADRENERGIC INHIBITOR AND A LINKER AND METHODS OF MAKING COMPOUNDS HAVING A BETA-ADRENERGIC INHIBITOR, A LINKER AND A PHOSPHODIESTERASE INHIBITOR". Page/Page column 56-57. . Retrieved 2008/12/05.