57260-67-0 Usage
Description
1-(3,4-Dichlorophenyl)piperazine, an N-substituted piperazine, is a pale yellow crystalline powder with a freezing point of 335.65K and a boiling point of 643.73K. It has a density of 1.2949g/cm3 and a refractive index of 1.6400 at 25°C.
Uses
1. Used in Pharmaceutical Industry:
1-(3,4-Dichlorophenyl)piperazine is used as an intermediate compound for the synthesis of various pharmaceutical drugs. Its unique chemical structure allows it to be a key component in the development of medications targeting specific conditions.
2. Used in Chemical Research:
As a versatile chemical compound, 1-(3,4-Dichlorophenyl)piperazine is used as a research tool in the field of chemistry. It aids in understanding the properties and reactions of N-substituted piperazines, contributing to the advancement of chemical knowledge and potential applications.
3. Used in Material Science:
The specific physical and chemical properties of 1-(3,4-Dichlorophenyl)piperazine make it a candidate for use in material science, potentially for the development of new materials with unique properties or for improving existing materials.
4. Used in Analytical Chemistry:
Due to its distinct characteristics, 1-(3,4-Dichlorophenyl)piperazine can be employed as a reference compound or standard in analytical chemistry for calibration and quality control purposes, ensuring accurate measurements and analysis in various chemical processes.
Check Digit Verification of cas no
The CAS Registry Mumber 57260-67-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,2,6 and 0 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 57260-67:
(7*5)+(6*7)+(5*2)+(4*6)+(3*0)+(2*6)+(1*7)=130
130 % 10 = 0
So 57260-67-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H12Cl2N2/c11-9-2-1-8(7-10(9)12)14-5-3-13-4-6-14/h1-2,7,13H,3-6H2/p+1
57260-67-0Relevant articles and documents
MONOACYLGLYCEROL LIPASE INHIBITORS
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Paragraph 0111-0112; 0141; 0153-0154; 0208-0209, (2021/09/09)
Provided are compounds of formula (I), or a pharmaceutically acceptable salt or solvate thereof: Also provided are compositions comprising compounds of formula (I). The compounds and compositions are also provided for use as medicaments, for example as medicaments useful in the treatment of a condition modulated by monoacylglycerol lipase (MAGL). Also provided are the use of compounds and compositions for the inhibition of monoacylglycerol lipase (MAGL).
Discovery of imidazole carboxamides as potent and selective CCK1R agonists
Zhu, Cheng,Hansen, Alexa R.,Bateman, Thomas,Chen, Zhesheng,Holt, Tom G.,Hubert, James A.,Karanam, Bindhu V.,Lee, Susan J.,Pan, Jie,Qian, Su,Reddy, Vijay B.G.,Reitman, Marc L.,Strack, Alison M.,Tong, Vincent,Weingarth, Drew T.,Wolff, Michael S.,MacNeil, Doug J.,Weber, Ann E.,Duffy, Joseph L.,Edmondson, Scott D.
scheme or table, p. 4393 - 4396 (2009/04/06)
High-throughput screening revealed diaryl pyrazole 3 as a selective albeit modest cholecystokinin 1 receptor (CCK1R) agonist. SAR studies led to the discovery and optimization of a novel class of 1,2-diaryl imidazole carboxamides. Compound 44, which was profiled extensively, showed good in vivo mouse gallbladder emptying (mGBE) and lean mouse overnight food intake (ONFI) reduction activities.
Tetracyclic benzimidazole derivatives and combinatorial libraries thereof
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, (2008/06/13)
The present invention relates to novel tetracyclic benzimidazole derivative compounds of the following formula: wherein R1to R10have the meanings described in here. The invention further relates to combinatorial libraries containing two or more such compounds, as well as methods of preparing tetracyclic benzimidazole derivative compounds.
