Technology Process of 2-Cyclohexen-1-one, 4-(2,3-dimethoxyphenyl)-3-ethenyl-4-methyl-
There total 6 articles about 2-Cyclohexen-1-one, 4-(2,3-dimethoxyphenyl)-3-ethenyl-4-methyl- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 51 percent / n-BuLi / tetrahydrofuran; hexane / 1.) 0 deg C, 3 h, 2.) room temperature, 8 h
2: 60 percent / Jones reagent / acetone / 1 h / 0 °C
3: NaH / tetrahydrofuran / 1.) 0 deg C to room temperature, 30 min, 2.) 0 deg C, 1 h; room temperature, 4 h
4: 1.25 g / t-BuOK / tetrahydrofuran / 1.) 30 min, 2.) 3 d
5: 96 percent / p-TsOH / 2 h / Heating
6: 1.) cerium chloride, 2.) 2percent HCl / 1.) THF, room temperature, 4 h, 2.) 20 min
With
hydrogenchloride; n-butyllithium; jones reagent; cerium(III) chloride; potassium tert-butylate; sodium hydride; toluene-4-sulfonic acid;
In
tetrahydrofuran; hexane; acetone;
DOI:10.1021/jo970570q
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 60 percent / Jones reagent / acetone / 1 h / 0 °C
2: NaH / tetrahydrofuran / 1.) 0 deg C to room temperature, 30 min, 2.) 0 deg C, 1 h; room temperature, 4 h
3: 1.25 g / t-BuOK / tetrahydrofuran / 1.) 30 min, 2.) 3 d
4: 96 percent / p-TsOH / 2 h / Heating
5: 1.) cerium chloride, 2.) 2percent HCl / 1.) THF, room temperature, 4 h, 2.) 20 min
With
hydrogenchloride; jones reagent; cerium(III) chloride; potassium tert-butylate; sodium hydride; toluene-4-sulfonic acid;
In
tetrahydrofuran; acetone;
DOI:10.1021/jo970570q
- Guidance literature:
-
Multi-step reaction with 4 steps
1: NaH / tetrahydrofuran / 1.) 0 deg C to room temperature, 30 min, 2.) 0 deg C, 1 h; room temperature, 4 h
2: 1.25 g / t-BuOK / tetrahydrofuran / 1.) 30 min, 2.) 3 d
3: 96 percent / p-TsOH / 2 h / Heating
4: 1.) cerium chloride, 2.) 2percent HCl / 1.) THF, room temperature, 4 h, 2.) 20 min
With
hydrogenchloride; cerium(III) chloride; potassium tert-butylate; sodium hydride; toluene-4-sulfonic acid;
In
tetrahydrofuran;
DOI:10.1021/jo970570q