9-HYDROXYPELARGONIC ACID METHYL ESTER

Base Information

• Chemical Name: 9-HYDROXYPELARGONIC ACID METHYL ESTER
• CAS No.: 34957-73-8
• Molecular Formula: C10H20 O3
• Molecular Weight: 188.267
• Hs Code.: 2918199090
• Mol file: 34957-73-8.mol

Synonyms:8-Methoxycarbonyloctan-1-ol;8-Methoxycarbonyloctanol; 9-Hydroxynonanoic acid methyl ester; Methyl9-hydroxynonanoate; NSC 159261

Chemical Property of 9-HYDROXYPELARGONIC ACID METHYL ESTER

Chemical Property:

• Refractive Index: 1.4430 to 1.4460
• Boiling Point: 258.2°Cat760mmHg
• PKA: 15.19±0.10(Predicted)
• Flash Point: 97.5°C
• PSA: 46.53000
• Density: 0.967g/cm³
• LogP: 1.88240
• Storage Temp.: Refrigerator
• Solubility.: Chloroform, Ethyl Acetate

Purity/Quality:

98%,99%, ^*data from raw suppliers

8-Methoxycarbonyloctanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 8-Methoxycarbonyloctanol (cas# 34957-73-8) is a compound useful in organic synthesis.

Technology Process of 9-HYDROXYPELARGONIC ACID METHYL ESTER

There total 4 articles about 9-HYDROXYPELARGONIC ACID METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

methanol (67-56-1) + 9-hydroxynonanoic acid (3788-56-5) → methyl 9-hydroxynonanoate (34957-73-8)

Guidance literature:

With sulfuric acid; for 4h; Heating;

DOI:10.1021/jo00233a037

Reference yield: 35.0%

methyl 9-chloro-9-oxononanoate (56555-02-3) → azelaic acid (123-99-9,26776-28-3) + Dimethyl azelate (1732-10-1) + methyl 9-hydroxynonanoate (34957-73-8)

Guidance literature:

With sodium tetrahydroborate;

DOI:10.1021/jo00233a037

Reference yield:

Methyl oleate (112-62-9) → methyl 9-hydroxynonanoate (34957-73-8) + nonyl alcohol (143-08-8)

Guidance literature:

With dimethylsulfide borane complex; ozone; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts; 1.) CH₂Cl₂, -78 deg C, 2.) 22 deg C, 24 h;

DOI:10.1021/jo00267a035

upstream raw materials:

methanol

9-hydroxynonanoic acid

Methyl oleate

methyl 9-chloro-9-oxononanoate

Downstream raw materials:

9-hydroxynonanoic acid

methyl ester of azelaic acid aldehyde

9-(2-Nitro-phenylselanyl)-nonanoic acid methyl ester

8-methoxycarbonyloctyl-3,4,6-tri-O-acetyl-2-O-benzyl-α-D-glucopyranoside

Refernces

• 1、 Yamamoto, Nobuyuki,Obora, Yasushi,Ishii, Yasutaka. "Iridium-catalyzed oxidative methyl esterification of primary alcohols and diols with methanol". experimental part. p. 2937 - 2941. Retrieved 2011/05/30.
• 2、 Flippin, Lee A.,Gallagher, David W.,Jalali-Araghi, Keyvan. "A Convenient Method for the Reduction of Ozonides to Alcohols with Borane-Dimethyl Sulfide Complex". . p. 1430 - 1432. Retrieved 2007/10/02.