4-Bromobutylazanium;bromide

Base Information

• Chemical Name: 4-Bromobutylazanium;bromide
• CAS No.: 24566-81-2
• Molecular Formula: C4H10 Br N . Br H
• Molecular Weight: 232.946
• Hs Code.: 2921199090
• Mol file: 24566-81-2.mol

Synonyms:

Chemical Property of 4-Bromobutylazanium;bromide

Chemical Property:

• Vapor Pressure: 1.13mmHg at 25°C
• Melting Point: 151-154 °C(Solv: ethyl acetate (141-78-6))
• Boiling Point: 175.8°Cat760mmHg
• Flash Point: 60.1°C
• PSA: 26.02000
• Density: 1.364g/cm³
• LogP: 2.77860
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 232.92378
• Heavy Atom Count: 7
• Complexity: 23.5

Purity/Quality:

99%, ^*data from raw suppliers

4-Bromobutan-1-amineHydrobromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CCBr)C[NH3+].[Br-]
• Uses: 4-Bromobutan-1-amine is an intermediate used to prepare primary aminoalkanethiosulfuric acids as potential antiradiation agents.

Technology Process of 4-Bromobutylazanium;bromide

There total 2 articles about 4-Bromobutylazanium;bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

4-Aminobutanol (13325-10-5) → 4-bromo-n-butan-1-amine hydrobromide (24566-81-2)

Guidance literature:

With hydrogen bromide; In benzene; for 2h; Heating;

DOI:10.1002/jhet.5570370605

Reference yield:

4-phenoxybutylamine (16728-66-8) → 4-bromo-n-butan-1-amine hydrobromide (24566-81-2)

Guidance literature:

With hydrogen bromide; In water; for 6h; Heating;

DOI:10.1080/00304940309355861

Reference yield: 95.0%

4-bromo-n-butan-1-amine hydrobromide (24566-81-2) + benzyl chloroformate (501-53-1,94274-21-2) → N-[(phenylmethoxy)carbonyl]-4-bromobutylamine (101625-10-9)

Guidance literature:

With potassium carbonate; In 1,4-dioxane; water; at 20 ℃; for 1.5h; pH=6 - 8;

DOI:10.1021/jo000926p

upstream raw materials:

4-Aminobutanol

4-phenoxybutylamine

Downstream raw materials:

1-amino-5-hexyne

Thioschwefelsaeure-S-(4-amino-butylester)

Methanesulfonic acid 4-[(E)-2-(4-bromo-butylcarbamoyl)-vinyl]-phenyl ester

Methanesulfonic acid 4-[(E)-2-(4-bromo-butylcarbamoyl)-vinyl]-2-methoxy-phenyl ester

Refernces

• 1、 Larraufie, Marie-Hélène,Malacria, Max,Courillon, Christine,Ollivier, Cyril,Fensterbank, Louis,Lac?te, Emmanuel. "Synthesis of natural quinazolinones and some of their analogues through radical cascade reactions involving N-acylcyanamides". . p. 7699 - 7705. Retrieved 2013/08/23.
• 2、 Hedrera,Perillo. "1H-4,5,6,7-tetrahydro-1,3-diazepines. Part I: Synthesis, spectral and chemical properties of 1,2-diaryl derivatives". . p. 1431 - 1438. Retrieved 2007/10/03.