2,7-Diamino-9H-fluoren-9-one

Base Information

• Chemical Name: 2,7-Diamino-9H-fluoren-9-one
• CAS No.: 2915-84-6
• Molecular Formula: C13H10 N2 O
• Molecular Weight: 210.235
• European Community (EC) Number: 631-096-8
• NSC Number: 107568
• DSSTox Substance ID: DTXSID10183414
• Nikkaji Number: J80.592K
• Wikidata: Q83054205
• ChEMBL ID: CHEMBL2442435
• Mol file: 2915-84-6.mol

Synonyms:2,7-Diamino-9H-fluoren-9-one;2,7-DIAMINO-9-FLUORENONE;2915-84-6;2,7-diaminofluoren-9-one;9H-Fluoren-9-one, 2,7-diamino-;CHEMBL2442435;NSC107568;2,7-Diaminofluoren-9-on;SCHEMBL864582;YSCK0219;DTXSID10183414;2,7-diamino-9H-fluorene-9-one;BDBM50134203;AKOS015997066;NSC 107568;NSC-107568;SB78944;BS-51611;CS-0311800;E77014

Chemical Property of 2,7-Diamino-9H-fluoren-9-one

Chemical Property:

• Vapor Pressure: 3.53E-11mmHg at 25°C
• Boiling Point: 526.6°Cat760mmHg
• Flash Point: 272.3°C
• PSA: 69.11000
• Density: 1.407g/cm³
• LogP: 3.22480
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 210.079312947
• Heavy Atom Count: 16
• Complexity: 276

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,7-DIAMINO-9-FLUORENONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C=C1N)C(=O)C3=C2C=CC(=C3)N

Technology Process of 2,7-Diamino-9H-fluoren-9-one

There total 10 articles about 2,7-Diamino-9H-fluoren-9-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2,7-dinitro-9-fluorenone (31551-45-8) → 2,7-diaminofluoren-9-one (2915-84-6)

Guidance literature:

With 5%-palladium/activated carbon; hydrogen; In methanol;

Reference yield: 96.0%

2,7-fluorenediamine (525-64-4) → 2,7-diaminofluoren-9-one (2915-84-6)

Guidance literature:

With air; caesium carbonate; In dimethyl sulfoxide; at 20 ℃; for 16h;

DOI:10.1055/s-2006-950189

Reference yield:

hydrated stannous chloride + 2,7-dinitro-9-fluorenone (31551-45-8) → 2,7-diaminofluoren-9-one (2915-84-6)

Guidance literature:

With hydrogenchloride; sodium hydroxide; acetic acid; In water;

upstream raw materials:

2,7-dinitro-9-fluorenone

9-Oxo-2-amino-7-nitrofluorene

2,7-fluorenediamine

2-nitro-9H-fluoren-9-one

Downstream raw materials:

3,8-diamino-phenanthridin-6-ol

3,8-diaminophenanthridone

2,7-difluoro-9-fluorenone

2,7-di[(p-trimethylsilylethynylphenyl)ethynyl]fluoren-9-one

Refernces

• 1、 Lee, Chia-Chung,Chang, Deh-Ming,Huang, Kuo-Feng,Chen, Chun-Liang,Chen, Tsung-Chih,Lo, Yang,Guh, Jih-Hwa,Huang, Hsu-Shan. "Design, synthesis and antiproliferative evaluation of fluorenone analogs with DNA topoisomerase i inhibitory properties". . p. 7125 - 7133. Retrieved 2013.
• 2、 Arafa, Reem K.,Brun, Reto,Wenzler, Tanja,Tanious, Farial A.,Wilson, W. David,Stephens, Chad E.,Boykin, David W.. "Synthesis, DNA affinity, and antiprotozoal activity of fused ring dicationic compounds and their prodrugs". . p. 5480 - 5488. Retrieved 2005.
• 3、 Alvi, Shakeel,Ali, Rashid. "An expeditious and highly efficient synthesis of substituted pyrroles using a low melting deep eutectic mixture". . p. 9732 - 9745. Retrieved 2021/12/01.
• 4、 -. "COMPOSITIONS AND METHODS OF MAKING EXPANDED HEMATOPOIETIC STEM CELLS USING DERIVATIVES OF FLUORENE". Paragraph 0400. . Retrieved 2019/05/15.