Di-o-tolylmethanimine

Base Information

• Chemical Name: Di-o-tolylmethanimine
• CAS No.: 22627-01-6
• Molecular Formula: C15H15N
• Molecular Weight: 209.291
• DSSTox Substance ID: DTXSID20877756
• Nikkaji Number: J1.606.032A
• Wikidata: Q82859612
• Mol file: 22627-01-6.mol

Synonyms:di-o-tolylmethanimine;22627-01-6;SCHEMBL4441911;DTXSID20877756;BYDWDILBVQYBHS-UHFFFAOYSA-N;O,O'-DIMETHYLBENZOPHENONEIMINE

Chemical Property of Di-o-tolylmethanimine

Chemical Property:

• XLogP3: 3.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 209.120449483
• Heavy Atom Count: 16
• Complexity: 222

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC=CC=C1C(=N)C2=CC=CC=C2C

Technology Process of Di-o-tolylmethanimine

There total 1 articles about Di-o-tolylmethanimine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Methylbenzonitrile (529-19-1) + 2-methylphenyl bromide (95-46-5) → bis(2-methylphenyl)methanimine (22627-01-6)

Guidance literature:

2-methylphenyl bromide; With iodine; magnesium; In tetrahydrofuran; for 3h; Inert atmosphere; Reflux;

2-Methylbenzonitrile; In tetrahydrofuran; for 24h; Inert atmosphere; Reflux;

DOI:10.1021/ja408864c

Reference yield: 82.0%

bis(2-methylphenyl)methanimine (22627-01-6) → 2,2'-dimethylbenzophenone (1018-97-9)

Guidance literature:

bis(2-methylphenyl)methanimine; With hydrogenchloride; water; In propan-1-ol; at 20 ℃; for 16h;

With sodium hydroxide; water; In propan-1-ol;

Reference yield: 78.0%

bis(2-methylphenyl)methanimine (22627-01-6) + diphenyl acetylene (501-65-5) → 8-methyl-3,4-diphenyl-1-(o-tolyl)-3,4-dihydroisoquinoline

Guidance literature:

With triiron dodecarbonyl; In diethyl ether; at 120 ℃; for 24h; Inert atmosphere; Schlenk technique;

DOI:10.1002/anie.201600365

upstream raw materials:

2-Methylbenzonitrile

2-methylphenyl bromide

Downstream raw materials:

2,2'-dimethylbenzophenone

2,2'-dimethylbenzhydrylamine

N-(2-Dimethylaminoethyl)-2,2'-dimethyl-diphenylketoimin

N-(3-Dimethylaminopropyl)-2,2'-dimethyl-diphenylketoimin

Refernces

• 1、 Chu, Ling,Wang, Xiao-Chen,Moore, Curtis E.,Rheingold, Arnold L.,Yu, Jin-Quan. "Pd-catalyzed enantioselective C-H iodination: Asymmetric synthesis of chiral diarylmethylamines". supporting information. p. 16344 - 16347. Retrieved 2013/12/04.