11-hydroxybimol.cyclic ester ;;

Base Information

• Chemical Name: 11-hydroxybimol.cyclic ester
• CAS No.: 659-77-8
• Molecular Formula: C₂₂H₄₀O₄
• Molecular Weight: 368.557
• Mol file: 659-77-8.mol

Synonyms:

Chemical Property of 11-hydroxybimol.cyclic ester ;;

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 11-hydroxybimol.cyclic ester ;;

There total 12 articles about 11-hydroxybimol.cyclic ester ;; which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

(10-carboxydecyl)diphenylsulfonium perchlorate → oxacyclododecan-2-one (1725-03-7) + 1,13-dioxa-cyclotetracosane-2,14-dione (659-77-8)

Guidance literature:

With potassium carbonate; In acetone; for 12h; Heating;

DOI:10.1021/jo00283a010

Reference yield: 78.0%

11-hydroxyundecanoic acid (3669-80-5) → oxacyclododecan-2-one (1725-03-7) + 1,13-dioxa-cyclotetracosane-2,14-dione (659-77-8)

Guidance literature:

With p-nitrobenzoic anhydride; scandium tris(trifluoromethanesulfonate); In tetrahydrofuran; acetonitrile; Heating;

DOI:10.1021/jo952237x

Reference yield: 71.0%

methyl 11-hydroxyundecanoate (24724-07-0) → oxacyclododecan-2-one (1725-03-7) + 1,13-dioxa-cyclotetracosane-2,14-dione (659-77-8)

Guidance literature:

With dimethyl aluminum selenide; In toluene; for 28h; Reflux;

DOI:10.1002/ejoc.201001201

upstream raw materials:

11-hydroxyundecanoic acid

11-bromoundecanoic acid

11-iodo-undecanoic acid

Acrylic acid 8-iodo-octyl ester

Refernces

• 1、 Shen, Liu-Lan,Mun, Han-Seo,Jeong, Jin-Hyun. "Macrocyclisation of macrodiolide with dimethylaluminium methaneselenolate". scheme or table. p. 6895 - 6899. Retrieved 2011/02/24.
• 2、 Oohashi, Yoshiaki,Fukumoto, Kentarou,Mukaiyama, Teruaki. "A new method for the synthesis of carboxylic esters and lactones with di-2-thienyl carbonate (2-DTC) by the promotion of DMAP and iodine". . p. 1508 - 1519. Retrieved 2007/10/03.