Technology Process of 18-Bromooctadecanoic acid
There total 5 articles about 18-Bromooctadecanoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
Jones reagent;
In
water; acetone;
for 1.25h;
Cooling;
- Guidance literature:
-
With
hydrogen bromide;
In
water; acetic acid;
for 18h;
Reflux;
DOI:10.1002/ejoc.200900645
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: toluene-4-sulfonic acid / tetrahydrofuran / 20 °C
2.1: magnesium; iodine / tetrahydrofuran / 65 °C
2.2: 0 °C
3.1: methanesulfonyl chloride; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 1 h / Inert atmosphere; Cooling with ice
3.2: Reflux
4.1: Jones reagent / water; acetone / 1.25 h / Cooling
With
Jones reagent; iodine; toluene-4-sulfonic acid; magnesium; methanesulfonyl chloride; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; water; acetone;
