3,7,11-Trimethyl-2,6,10-dodecatrienylmalonic acid diethyl ester

Base Information

• Chemical Name: 3,7,11-Trimethyl-2,6,10-dodecatrienylmalonic acid diethyl ester
• CAS No.: 26732-80-9
• Molecular Formula: C₂₂H₃₆O₄
• Molecular Weight: 364.525
• Mol file: 26732-80-9.mol

Synonyms:2-((2Z,6Z)-3,7,11-Trimethyl-dodeca-2,6,10-trienyl)-malonic acid diethyl ester;Farnesyl-malonsaeure-diethylester;3,7,11-Trimethyl-2,6,10-dodecatrienylmalonic acid diethyl ester;Farneylmalonsaeurediethylester;Ethyl 2-carbethoxy-farnesylacetat;

Chemical Property of 3,7,11-Trimethyl-2,6,10-dodecatrienylmalonic acid diethyl ester

Chemical Property:

• Boiling Point: 158 - 160 °C (0.2 mmHg)
• PSA: 52.60000
• LogP: 5.53810

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,7,11-Trimethyl-2,6,10-dodecatrienylmalonic acid diethyl ester

There total 2 articles about 3,7,11-Trimethyl-2,6,10-dodecatrienylmalonic acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

farnesol (4602-84-0) + methanetricarboxylic acid triethyl ester (6279-86-3) → (4E/Z,8E)-Farnesylmalonic diethyl ester (26732-80-9,58456-68-1,58456-69-2,58456-70-5,58456-71-6)

Guidance literature:

at 180 - 195 ℃;

Reference yield:

→ 1,1-Dicarbaethoxy-4,8,12-trimethyl-trideca-3,7,11-trien (26732-80-9)

Guidance literature:

Isomerengemisch (DEFM I-IV) nach Lit. 2;

Reference yield:

Geraniol (106-24-1) + (4E/Z,8E)-Farnesylmalonic diethyl ester (26732-80-9,58456-68-1,58456-69-2,58456-70-5,58456-71-6) → (4Z,8E)-Farnesylacetic acid geranyl ester (30462-48-7) + gefarnate (51-77-4)

Guidance literature:

at 185 - 190 ℃; for 8h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1007/BF00758769

upstream raw materials:

farnesol

methanetricarboxylic acid triethyl ester

Downstream raw materials:

(4Z,8E)-Farnesylacetic acid geranyl ester

gefarnate

(4E,8Z)-5,9,13-Trimethyl-tetradeca-4,8,12-trienoic acid ethyl ester