(4Z,8E)-Farnesylacetic acid geranyl ester

Base Information

• Chemical Name: (4Z,8E)-Farnesylacetic acid geranyl ester
• CAS No.: 30462-48-7
• Molecular Formula: C₂₇H₄₄O₂
• Molecular Weight: 400.645
• Mol file: 30462-48-7.mol

Synonyms:(4Z,8E)-Farnesylacetic acid geranyl ester

Chemical Property of (4Z,8E)-Farnesylacetic acid geranyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4Z,8E)-Farnesylacetic acid geranyl ester

There total 3 articles about (4Z,8E)-Farnesylacetic acid geranyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Geraniol (106-24-1) + (4E/Z,8E)-Farnesylmalonic diethyl ester (26732-80-9,58456-68-1,58456-69-2,58456-70-5,58456-71-6) → (4Z,8E)-Farnesylacetic acid geranyl ester (30462-48-7) + gefarnate (51-77-4)

Guidance literature:

at 185 - 190 ℃; for 8h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1007/BF00758769

Reference yield:

5,9,13-trimethyl-tetradeca-4,8,12-trienoic acid (23224-49-9) → Farnesylessigsaeure-geranylester (51-77-4,16898-88-7,30462-45-4,30462-46-5,30462-48-7)

Guidance literature:

Multi-step reaction with 2 steps

1: SOCl₂ / benzene

2: PhNMe₂ / benzene

With thionyl chloride; N,N-dimethyl-aniline; In benzene;

DOI:10.1021/jm00340a030

Reference yield:

Geraniol (106-24-1) + 5,9,13-Trimethyl-4,8,12-tetradecatrienoylchlorid (22128-24-1) → Farnesylessigsaeure-geranylester (51-77-4,16898-88-7,30462-45-4,30462-46-5,30462-48-7)

Guidance literature:

With N,N-dimethyl-aniline; In benzene;

DOI:10.1021/jm00340a030

upstream raw materials:

Geraniol

(4E/Z,8E)-Farnesylmalonic diethyl ester

5,9,13-Trimethyl-4,8,12-tetradecatrienoylchlorid

5,9,13-trimethyl-tetradeca-4,8,12-trienoic acid

Refernces

• 1、 CARDANI,CAVALLERI,ADAMI. "ESTERS OF FARNESYLACETIC ACID.". . p. 457 - 458. Retrieved 2007/10/12.