5H-Cyclopenta[b]pyridine

Base Information

• Chemical Name: 5H-Cyclopenta[b]pyridine
• CAS No.: 270-91-7
• Molecular Formula: C8H7N
• Molecular Weight: 117.14800
• Mol file: 270-91-7.mol

Synonyms:

Chemical Property of 5H-Cyclopenta[b]pyridine

Chemical Property:

• Boiling Point: 223.3±9.0 °C(Predicted)
• PKA: 5.15±0.20(Predicted)
• PSA: 12.89000
• Density: 1.115±0.06 g/cm3(Predicted)
• LogP: 1.65090

Purity/Quality:

97% ^*data from raw suppliers

5H-CYCLOPENTA[B]PYRIDINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5H-Cyclopenta[b]pyridine

There total 9 articles about 5H-Cyclopenta[b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6,7-dihydro-5H-cyclopenta[b]pyridin-7-yl acetate (90685-59-9) → 5H-1-pyrindine (270-91-7) + 7H-cyclopenta[b]pyridine (270-92-8)

Guidance literature:

With sulfuric acid; at 125 ℃; for 2h; Title compound not separated from byproducts;

DOI:10.1039/c39840000265

Reference yield:

7-hydroxy-6,7-dihydro-5H-cyclopenta[b]pyridine (41598-71-4) → 5H-1-pyrindine (270-91-7)

Guidance literature:

With sulfuric acid; at 130 ℃;

DOI:10.1021/ja01556a023

Reference yield:

6,7-dihydro-5H-cyclopenta[b]pyridin-7-yl acetate (90685-59-9) → 5H-1-pyrindine (270-91-7)

Guidance literature:

With sulfuric acid; at 130 ℃;

DOI:10.1021/ja01556a023

upstream raw materials:

7-hydroxy-6,7-dihydro-5H-cyclopenta[b]pyridine

6,7-dihydro-5H-cyclopenta[b]pyridin-7-yl acetate

2,3-cyclopentenopyridine

6,7-dihydro-5H-cyclopenta[b]pyridine 1-oxide

Refernces

• 1、 -. "DERIVATIVES OF AMINOINDANES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS". Page/Page column 45-46. . Retrieved 2011/10/03.
• 2、 Giam, C. S.,Ambrozich, Deborah. "A New Approach to the Preparation of 1,6- and 1,7-Naphthyridines". . p. 265 - 266. Retrieved 2007/10/02.