N-(2-Thienylmethyl)-2-thiophenemethanamine

Base Information

• Chemical Name: N-(2-Thienylmethyl)-2-thiophenemethanamine
• CAS No.: 58703-21-2
• Molecular Formula: C10H11NS2
• Molecular Weight: 209.336
• Hs Code.: 2934999090
• Mol file: 58703-21-2.mol

Synonyms:NSC 74406

Chemical Property of N-(2-Thienylmethyl)-2-thiophenemethanamine

Chemical Property:

• Vapor Pressure: 0.000657mmHg at 25°C
• Refractive Index: 1.628
• Boiling Point: 309 °C at 760 mmHg
• Flash Point: 140.7 °C
• PSA: 68.51000
• Density: 1.226 g/cm³
• LogP: 3.49030
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 209.03329170
• Heavy Atom Count: 13
• Complexity: 270

Purity/Quality:

99% ^*data from raw suppliers

bis(thiophen-2-ylmethyl)amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C=CSC(=C1)NC2=CCC=CS2

Technology Process of N-(2-Thienylmethyl)-2-thiophenemethanamine

There total 5 articles about N-(2-Thienylmethyl)-2-thiophenemethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

thiophene-2-carbonitrile (1003-31-2) → bis(thiophen-2-ylmethyl)amine hydrochloride (58703-21-2)

Guidance literature:

With sodium tetrahydroborate; La_0.5Ca_0.5CoO₃; In methanol; at 40 ℃; for 1.5h; under 760.051 Torr; chemoselective reaction;

DOI:10.4067/S0717-97072017000100005

Reference yield:

thiophene-2-carbaldehyde (98-03-3) → 2-Aminomethylthiophene (27757-85-3) + bis(thiophen-2-ylmethyl)amine hydrochloride (58703-21-2)

Guidance literature:

With ammonium hydroxide; hydrogen; nickel;

DOI:10.1021/jm0210818

Reference yield:

thiophene (188290-36-0,8014-23-1,25233-34-5) → 2-Aminomethylthiophene (27757-85-3) + bis(thiophen-2-ylmethyl)amine hydrochloride (58703-21-2)

Guidance literature:

With formaldehyd; ammonium chloride; acetic acid; anschliessendes Behandeln mit Methanol;

DOI:10.1021/ja01192a014

upstream raw materials:

thiophene

formaldehyd

thiophene-2-carbaldehyde

thiophene-2-carbonitrile

Downstream raw materials:

1,2-bis(thiophen-2-yl)ethane

2-((bis(thiophen-2-ylmethyl)amino)methyl)-4,6-di-tert-butylphenol

Refernces

• 1、 Bavandi, Hossein,Shiri, Ali,Tavakkoli, Haman. "Nano-sized La0.5Ca0.5CoO3-mediated reduction by nabh4 of aryl nitriles to bis-(benzyl) amines". . p. 3330 - 3334. Retrieved 2017/05/29.