1-(3-Phenylpropyl)naphthalene

Base Information

• Chemical Name: 1-(3-Phenylpropyl)naphthalene
• CAS No.: 29908-29-0
• Molecular Formula: C19H18
• Molecular Weight: 246.352
• DSSTox Substance ID: DTXSID30540449
• Wikidata: Q82416469
• Mol file: 29908-29-0.mol

Synonyms:1-(3-Phenylpropyl)naphthalene;29908-29-0;DTXSID30540449

Chemical Property of 1-(3-Phenylpropyl)naphthalene

Chemical Property:

• XLogP3: 6.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 4
• Exact Mass: 246.140850574
• Heavy Atom Count: 19
• Complexity: 251

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CCCC2=CC=CC3=CC=CC=C32

Technology Process of 1-(3-Phenylpropyl)naphthalene

There total 18 articles about 1-(3-Phenylpropyl)naphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

N,N,N-trimethyl-1-naphthalenaminium trifluoromethanesulfonate (1351445-39-0) + 3-phenylpropylmagnesium bromide (1462-75-5) → 1-(α-naphthyl)-3-phenylpropane (29908-29-0)

Guidance literature:

With iron(III)-acetylacetonate; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; at 25 ℃; for 1h; Inert atmosphere; Schlenk technique;

DOI:10.1016/j.tet.2013.09.039

Reference yield: 99.0%

1-Fluoronaphthalene (321-38-0) + 3-phenylpropylmagnesium bromide (1462-75-5) → 1-(α-naphthyl)-3-phenylpropane (29908-29-0)

Guidance literature:

1-Fluoronaphthalene; With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; 1,2-bis-(diphenylphosphino)ethane; In di-isopropyl ether; for 0.05h; Sealed tube; Glovebox;

3-phenylpropylmagnesium bromide; In diethyl ether; di-isopropyl ether; at 100 ℃; for 24h; Sealed tube; Glovebox;

DOI:10.1021/acs.orglett.8b02351

Reference yield: 93.0%

diethyl naphthalen-1-yl phosphate (33650-14-5) + (3-phenylpropyl)magnesium chloride (54812-94-1) → 1-(α-naphthyl)-3-phenylpropane (29908-29-0)

Guidance literature:

With [1,3-bis(2,6-diisopropylphenyl)imidazolium][Fe(PCy₃)Br₃]; In tetrahydrofuran; at 0 - 85 ℃; for 8h; Schlenk technique; Inert atmosphere;

DOI:10.1039/c6dt02995g

upstream raw materials:

styrene

1-Methylnaphthalene

methanol

1-naphthylmethyl 3-phenylpropanoate

Downstream raw materials:

C₃₇H₃₄

C₃₇H₃₄

C₃₇H₃₄

C₃₇H₃₄

Refernces

• 1、 Lu, Zeye,Zheng, Qingshu,Yang, Siqi,Qian, Chun,Shen, Yajing,Tu, Tao. "NHC-Iridium-Catalyzed Deoxygenative Coupling of Primary Alcohols Producing Alkanes Directly: Synergistic Hydrogenation with Sodium Formate Generated in Situ". . p. 10796 - 10801. Retrieved 2021/09/08.
• 2、 Chen, Dengfeng,Fu, Yuanyuan,Cao, Xiaoji,Luo, Jinyue,Wang, Fei,Huang, Shenlin. "Metal-Free Cyclopropanol Ring-Opening C(sp3)-C(sp2) Cross-Couplings with Aryl Sulfoxides". supporting information. p. 5600 - 5605. Retrieved 2019/08/01.